Owlv2,1 Term Printed Access Card For Campbell/farrell/mcdougal's Biochemistry, 9th
9th Edition
ISBN: 9781305962972
Author: Campbell, Mary K.; Farrell, Shawn O.; Mcdougal, Owen M.
Publisher: Cengage Learning
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Chapter 14, Problem 49RE
Interpretation Introduction
Interpretation:
The types of therapies that are used to fight AIDS are to be discussed.
Concept introduction:
HIV is the most notorious retrovirus, which causes acquired immunodeficiency syndrome (AIDS).
HIV has a single-stranded RNA that has various proteins arranged around it. A protein cover surrounds the assembly of RNA and protein, which gives it a shape of a truncated cone. HIV has various features that lead to its perseverance and lethality.
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The enzyme lactate dehydrogenase (LDH) catalyzes the conversion of pyruvate to lactatein skeletal muscle cells using NAD/NADH during anaerobic “balanced” fermentation.Answer the following questions about this reaction.
(a) Write out the two reductive half reactions and indicate the E ̊' for each half reaction. Write out the full balanced reaction for the pyruvate to lactate rxn and indicate the ∆E ̊' for the reaction.
(b) What is the free energy change under standard state conditions for thisreaction? Which direction is spontaneous?(c) Assume that in skeletal muscle cells the ratio of [NAD+] to [NADH] is 100, and that the[pyruvate] = 0.40 mM and [lactate] = 4.0 mM. What is the free energy change (∆G')for the conversion of pyruvate to lactate? Indicate the direction in which the reactionis spontaneous under these cellular conditions.
Why did the authors worry about the temperature-dependent solubility of the carriers in thebilayer? How did the authors determine whether the effect of freezing the lipid bilayer wasto decrease the solubility of the carriers (nonactin and valinomycin) or whether the effectwas to impair their ability to diffuse through the membrane (decrease their mobility)?
Kranse et. al. measured the temperature dependence of conductance using membranescontaining the phospholipids glyceryl dipalmitate and glyceryl distearate. Describe themodifications in membrane content that you would employ to:
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(b) make the ion conductance curve for valinomycin andnonactin more like that of gramicidin
Chapter 14 Solutions
Owlv2,1 Term Printed Access Card For Campbell/farrell/mcdougal's Biochemistry, 9th
Ch. 14 - Prob. 1RECh. 14 - Prob. 2RECh. 14 - Prob. 3RECh. 14 - Prob. 4RECh. 14 - Prob. 5RECh. 14 - Prob. 6RECh. 14 - Prob. 7RECh. 14 - REFLECT AND APPLY Some viruses can undergo lysis...Ch. 14 - REFLECT AND APPLY What might be the...Ch. 14 - Prob. 10RE
Ch. 14 - Prob. 11RECh. 14 - Prob. 12RECh. 14 - Prob. 13RECh. 14 - Prob. 14RECh. 14 - Prob. 15RECh. 14 - Prob. 16RECh. 14 - Prob. 17RECh. 14 - Prob. 18RECh. 14 - Prob. 19RECh. 14 - RECALL What is innate immunity? What is acquired...Ch. 14 - RECALL What are the components of innate immunity?Ch. 14 - Prob. 22RECh. 14 - Prob. 23RECh. 14 - RECALL What is clonal selection?Ch. 14 - Prob. 25RECh. 14 - Prob. 26RECh. 14 - Prob. 27RECh. 14 - Prob. 28RECh. 14 - Prob. 29RECh. 14 - BIOCHEMICAL CONNECTIONS Explain the mode of action...Ch. 14 - Prob. 31RECh. 14 - Prob. 32RECh. 14 - Prob. 33RECh. 14 - Prob. 34RECh. 14 - Prob. 35RECh. 14 - REFLECT AND APPLY Why is it inaccurate to say,...Ch. 14 - REFLECT AND APPLY Describe the difference between...Ch. 14 - Prob. 38RECh. 14 - Prob. 39RECh. 14 - Prob. 40RECh. 14 - Prob. 41RECh. 14 - BIOCHEMICAL CONNECTIONS Describe the positive and...Ch. 14 - Prob. 43RECh. 14 - Prob. 44RECh. 14 - Prob. 45RECh. 14 - Prob. 46RECh. 14 - Prob. 47RECh. 14 - Prob. 48RECh. 14 - Prob. 49RECh. 14 - Prob. 50RECh. 14 - Prob. 51RECh. 14 - Prob. 52RECh. 14 - Prob. 53RECh. 14 - Prob. 54RE
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