The mechanismsadopted by bacterial cellsto escape the deleterious effects of activated complement proteins. Introduction: The complement system is a key component belonging to the innate immune response thatplays a role in the recognition of the foreign agents and also in the activation of adaptive immunity. It consists of various complement proteins, which get activated by three main mechanisms:classical pathway, alternate pathway, and lectinpathway. Their activation eventually leads to the formation of the multiprotein pore complex or the MAC (membrane attack complex), which causes the cell lysis. Despite such elaborate machinery, various pathogens including bacteria are able to evade the immune system.

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Chapter 14, Problem 2CT

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The mechanismsadopted by bacterial cellsto escape the deleterious effects of activated complement proteins.

Introduction:

The complement system is a key component belonging to the innate immune response thatplays a role in the recognition of the foreign agents and also in the activation of adaptive immunity. It consists of various complement proteins, which get activated by three main mechanisms:classical pathway, alternate pathway, and lectinpathway. Their activation eventually leads to the formation of the multiprotein pore complex or the MAC (membrane attack complex), which causes the cell lysis. Despite such elaborate machinery, various pathogens including bacteria are able to evade the immune system.

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