Biological Science (6th Edition)
Biological Science (6th Edition)
6th Edition
ISBN: 9780321976499
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael
Publisher: PEARSON
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Chapter 14, Problem 26PIAT
Summary Introduction

To analyze:

The probability of the first child of the couple to have ALD (adrenoleukodystrophy).

Introduction:

Adrenoleukodystrophy is a type of X-linked disorder. It occurs as a result of mutation in the ABCD1 gene, which is present on the Xq28 chromosome. Furthermore, the nonfunctioning of these enzymes damages the myelin sheath present on the axon, which further causes degeneration of the neuron. In the given pedigree, the first daughter in the last generation is married to a man with no history of ALD in his family. Being a genetic counselor, advise the couple about chances of their first child having ALD. The pedigree is shown below:

Biological Science (6th Edition), Chapter 14, Problem 26PIAT

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