Biology: Life on Earth with Physiology Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)
Biology: Life on Earth with Physiology Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)
11th Edition
ISBN: 9780133910605
Author: Gerald Audesirk, Teresa Audesirk, Bruce E. Byers
Publisher: PEARSON
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Chapter 14, Problem 1MC
Summary Introduction

Introduction:

Single nucleotide polymorphism is caused by the change of an amino acid at a single position in the amino acid chain of the protein. It causes a change in the structure, conformation and molecular function of the protein.

Expert Solution & Answer
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Answer to Problem 1MC

Correct answer:

Translocation causes a change in the location of the gene on the chromosome locus whereas single nucleotide polymorphism is caused due to change of an amino acid at a single position in the polypeptide chain. Therefore, option (a) is correct.

Option (a) is given as “It is usually caused by a translocation mutation”.

Explanation of Solution

Justify reasons for the correct statement:

Single nucleotide polymorphism changes the structure, function and molecular mechanism of the protein due to an alteration of an amino-acid at a single position on the polypeptide chain.

Hence, option (a) is correct.

Justify reasons for the incorrect statements:

Option (b) is given as “It is usually caused by a nucleotide substitution mutation”. This mutation causes a change in the amino acid present at a specific position in the polypeptide leading to a change in the functioning mechanism of the protein. Hence, it is a wrong answer.

Option (c) is given as “It may change the phenotype of an organism”. The phenotype of an organism is changed due to change in the sequence of the nucleotide of the genes present on chromosomes. Hence, it is a wrong answer.

Option (d) is given as “It is inherited from parent to offspring”. Genes are inherited from parent to offspring. Hence, it is a wrong answer.

Hence, options (b), (c), and (d) are incorrect.

Conclusion

The statement which is not true regarding the single nucleotide polymorphism is that it is usually caused by a translocation mutation. Translocation mutation is caused due to the change in the chromosome locus of the gene under study whereas the single nucleotide polymorphism is caused due to the alteration and replacement of an amino-acid at a specific position of the polypeptide chain.

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Biology: Life on Earth with Physiology Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)

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