Chapter 13, Problem 69IP

Interpretation Introduction

Interpretation: The preparation of trans-2, and 3-diphenyloxirane needs to be explained using bromobenzene and ethylene oxide as carbon sources.

Concept Introduction: Grignard reagent can act as a strong base as well as a strong nucleophile. The nature of the reaction depends on the reactant that is if the possibility of an attack of nucleophile or elimination is more. In the case of epoxide, the Grignard reagent act as a nucleophile, and an attack on the electrophilic epoxide group takes place. In Williamson Ether Synthesis, ether is formed from deprotonated alcohol and an organohalide. The reaction takes place between a primary alkyl halide and an alkoxide ion via an SN2 mechanism.