ORGANIC CHEMISTRY (LL)-W/WILEYPLUS
ORGANIC CHEMISTRY (LL)-W/WILEYPLUS
4th Edition
ISBN: 9781119659556
Author: Klein
Publisher: WILEY
Question
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Chapter 13, Problem 30PP

(a)

Interpretation Introduction

Interpretation: The synthesis of the following compounds to be predicted by choosing effective reagents.

Concept Introduction:

Acidic cleavage of Ethers: Generally ethers are unreactive under basic or mildly acidic conditions. When the ethers are heated with a concentrated solution of a strong acid, ether will undergo acidic cleavage in which ether is converted into two alkyl halides.

HBr &HI Acids are used to cleave ether. HCl Is less effective, but HF acid does not cleave ethers due to the relative nucleophilicity of the halide ions.

Two step mechanistic ways:

  1. I. Proton transfer.
  2. II. Nucleophile attack via SN2 process

To Identify: The effective synthesis of the given compounds to be identified.

(b)

Interpretation Introduction

Interpretation: The synthesis of the following compounds to be predicted by choosing effective reagents.

Concept Introduction:

Acidic cleavage of Ethers: Generally ethers are unreactive under basic or mildly acidic conditions. When the ethers are heated with a concentrated solution of a strong acid, ether will undergo acidic cleavage in which ether is converted into two alkyl halides.

HBr &HI Acids are used to cleave ether. HCl Is less effective, but HF acid does not cleave ethers due to the relative nucleophilicity of the halide ions.

Two step mechanistic ways:

  1. I. Proton transfer.
  2. II. Nucleophile attack via SN2 process

To Identify: The effective synthesis of the given compounds to be identified.

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