EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
15th Edition
ISBN: 9781260163049
Author: Fox
Publisher: MCGRAW HILL BOOK COMPANY
Question
Book Icon
Chapter 13, Problem 27RA
Summary Introduction

To review:

The mechanism by which the coumarin drugs, heparin, aspirin and ethylenediaminetetraacetic acid (EDTA) act as anticoagulants and which of them are effective when added to any test tube.

Introduction:

Anticoagulant helps to prevent blood clot, it prevents blood cells from adhering together to form a clot. Aspirin, coumarin, (ethylenediaminetetraacetic acid (EDTA) and heparin are examples of anticoagulants.

Blurred answer
Students have asked these similar questions
Outline a method for using apomixis to maintain feminized CannabisAssume apomixis is controlled by a single dominant gene. You can choose the type of apomixis: obligate or facultative, gametophytic or sporophytic. Discuss advantages and disadvantages of your proposed method.
Kinetics: One-Compartment First-Order Absorption 1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.  Using this data and set of graphs, determine:(calculate for each variable) (a) k, C0, V, and AUC* for the bolus iv data  (b) k, ka, B1, and AUC* for the po data  c) k, ka, B1, and AUC* for the ip data  (d) relative bioavailability for po vs ip, Fpo/Fip  (e)absolute ip bioavailability, Fip  (f) absolute po bioavailability, Fpo
3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L.  Measurements from preliminary tests indicate the following human pharmacokinetic parameter values:  t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%.  Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax).  (c) Estimate the maximum plasma concentration (Cmax).  (d) Estimate the time at which the plasma level first rises above 30 mg/L.  (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L.  Hint:  based on part (a) it should be apparent that the answer is less than 1hr.)  (e)…

Chapter 13 Solutions

EBK HUMAN PHYSIOLOGY

Ch. 13 - Discuss how defective valves affect blood flow...Ch. 13 - Prob. 7bCPCh. 13 - Prob. 8aCPCh. 13 - Prob. 8bCPCh. 13 - Draw a figure to illustrate the pressure...Ch. 13 - Prob. 10aCPCh. 13 - Using a line diagram, illustrate a myocardial...Ch. 13 - Draw an ECG and label the waves. Indicate the...Ch. 13 - Draw a figure that shows the relationship between...Ch. 13 - Prob. 11cCPCh. 13 - Prob. 12aCPCh. 13 - Prob. 12bCPCh. 13 - Explain the functions of capillaries and describe...Ch. 13 - Prob. 14CPCh. 13 - Prob. 15CPCh. 13 - Identify normal and pathological causes of...Ch. 13 - Prob. 16bCPCh. 13 - Prob. 17aCPCh. 13 - Explain how the lymphatic system and the...Ch. 13 - Prob. 18CPCh. 13 - Prob. 1RACh. 13 - All arteries in the body contain oxygen-rich blood...Ch. 13 - The "lub," or first heart sound, is produced by...Ch. 13 - The first heart sound is produced at Ch. 13 - Changes in the cardiac rate primarily reflect...Ch. 13 - Prob. 6RACh. 13 - Prob. 7RACh. 13 - The cells that normally have the fastest rate of...Ch. 13 - Which of these statements is true? a. The heart...Ch. 13 - Prob. 10RACh. 13 - Prob. 11RACh. 13 - Prob. 12RACh. 13 - Prob. 13RACh. 13 - Prob. 14RACh. 13 - Prob. 15RACh. 13 - During the phase of isovolumetric relaxation of...Ch. 13 - Peristaltic waves of contraction move fluid within...Ch. 13 - Describe how the pacemaker cells produce a...Ch. 13 - What characteristic of the SA node distinguishes...Ch. 13 - Compare the duration of the heart's contraction...Ch. 13 - Step by step, describe the pressure changes that...Ch. 13 - Can a detective valve be detected by an ECG? Can a...Ch. 13 - Describe the causes of the P, QRS, and T waves of...Ch. 13 - The lungs are the only organs that receive the...Ch. 13 - Prob. 25RACh. 13 - Prob. 26RACh. 13 - Prob. 27RACh. 13 - Prob. 28RACh. 13 - Prob. 29RACh. 13 - Prob. 30RACh. 13 - Prob. 31RACh. 13 - Prob. 32RACh. 13 - Prob. 33RACh. 13 - Prob. 34RACh. 13 - Prob. 35RACh. 13 - Prob. 36RACh. 13 - Prob. 37RACh. 13 - Prob. 38RACh. 13 - Prob. 39RACh. 13 - Prob. 40RACh. 13 - Prob. 41RACh. 13 - Prob. 42RA
Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Surgical Tech For Surgical Tech Pos Care
Health & Nutrition
ISBN:9781337648868
Author:Association
Publisher:Cengage
Text book image
Basic Clinical Laboratory Techniques 6E
Biology
ISBN:9781133893943
Author:ESTRIDGE
Publisher:Cengage
Text book image
Principles Of Radiographic Imaging: An Art And A ...
Health & Nutrition
ISBN:9781337711067
Author:Richard R. Carlton, Arlene M. Adler, Vesna Balac
Publisher:Cengage Learning
Text book image
Curren'S Math For Meds: Dosages & Sol
Nursing
ISBN:9781305143531
Author:CURREN
Publisher:Cengage
Text book image
Essentials of Pharmacology for Health Professions
Nursing
ISBN:9781305441620
Author:WOODROW
Publisher:Cengage
Text book image
Comprehensive Medical Assisting: Administrative a...
Nursing
ISBN:9781305964792
Author:Wilburta Q. Lindh, Carol D. Tamparo, Barbara M. Dahl, Julie Morris, Cindy Correa
Publisher:Cengage Learning