
Concept explainers
A mutation removes a single base pair within the coding sequence of a gene and inactivates the protein encoded by the gene. Such a mutation is
- a silent mutation.
- a missense mutation.
- a nonsense mutation.
- a frameshift mutation.
- both b and c.

Introduction:
The mutation can be described as a condition in which the nucleotide sequence of the DNA is altered. Even a single change in nucleotide may result in many consequences.
Answer to Problem 1TY
Option (d).
Explanation of Solution
Explanation for Correct Answer:
Option (d) frameshift mutation. The frameshift mutation occurs due to a deletion or insertion of nucleotide, which is not a multiple of 3. It causes the shifting of the entire reading frame of DNA sequence, which is the reason it is named so. Sometimes, frameshift mutation may cause deletion of a nucleotide and resulting in a premature presence of stop codon and terminate the sequence prior resulting in short polypeptide or inactivation of the gene product. Hence, it is the correct answer.
Explanation for the incorrect answer:
Option (a) silent mutation. The silent mutation results in the change of nucleotide but does not affect the amino acid or protein formed by that. Hence, it is an incorrect answer.
Option (b) missense mutation. The missense mutation is a mutation that results in the change of nucleotide and replaces the amino acid in the protein sequence, but the length of the sequence remains unaffected. Hence, it is an incorrect answer.
Option (c) nonsense mutation. The non-sense mutations can be described as point mutation which results in the occurrence of a premature stop codon due to the replacement of a nucleotide. In this mutation, the presence of stop codon before the end of the sequence result in early termination of the amino acid formation and result in shorter polypeptide. Hence, it is an incorrect answer.
Option (e) both (b) and (c). As both the option (b) and (c)are incorrect answers, this is also an incorrect option.
Want to see more full solutions like this?
Chapter 13 Solutions
Principles of Biology
- Describe the principle of homeostasis.arrow_forwardExplain how the hormones of the glands listed below travel around the body to target organs and tissues : Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forwardWhat are the functions of the hormones produced in the glands listed below: Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forward
- Describe the hormones produced in the glands listed below: Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forwardPlease help me calculate drug dosage from the following information: Patient weight: 35 pounds, so 15.9 kilograms (got this by dividing 35 pounds by 2.2 kilograms) Drug dose: 0.05mg/kg Drug concentration: 2mg/mLarrow_forwardA 25-year-old woman presents to the emergency department with a 2-day history of fever, chills, severe headache, and confusion. She recently returned from a trip to sub-Saharan Africa, where she did not take malaria prophylaxis. On examination, she is febrile (39.8°C/103.6°F) and hypotensive. Laboratory studies reveal hemoglobin of 8.0 g/dL, platelet count of 50,000/μL, and evidence of hemoglobinuria. A peripheral blood smear shows ring forms and banana-shaped gametocytes. Which of the following Plasmodium species is most likely responsible for her severe symptoms? A. Plasmodium vivax B. Plasmodium ovale C. Plasmodium malariae D. Plasmodium falciparumarrow_forward
- please fill in missing parts , thank youarrow_forwardplease draw in the answers, thank youarrow_forwarda. On this first grid, assume that the DNA and RNA templates are read left to right. DNA DNA mRNA codon tRNA anticodon polypeptide _strand strand C с A T G A U G C A TRP b. Now do this AGAIN assuming that the DNA and RNA templates are read right to left. DNA DNA strand strand C mRNA codon tRNA anticodon polypeptide 0 A T G A U G с A TRParrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningHuman Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
- Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage LearningBiology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage LearningBiology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning





