Concept explainers
To explain: The reason behind an anaerobic condition when the cell could not discard pyruvate as a waste product.
Introduction: The cells growing in the absence of oxygen (anaerobic condition) in which the end product of glycolysis is pyruvate undergoes fermentation. In the process of fermentation, NAD+ is regenerated from NADH by transferring electron to organic molecule like lactate and ethanol.

Explanation of Solution
In the process of fermentation, in anaerobic condition of cell NAD+ is regenerated from NADH by transferring electron to organic molecule. To continue the process of glycolysis in the cell, cells need to regenerate NAD+. So, without the fermentation process there is no other methodical way to generate NAD+. In absence of NAD+, the glycolysis process is discontinued from the step- 6 that is energy generation phage where the oxidation of glyceraldehydes 3-phosphate produce 1, 3-biphosphoglycerate to continue the glycolysis process.
To explain: The products from glucose accumulate in the cell unable to generate either lactate or ethanol by fermentation.
Introduction: The cells growing in the absence of oxygen (anaerobic condition) in which the end product of glycolysis is pyruvate undergoes fermentation. In the process of fermentation, NAD+ is regenerated from NADH by transferring electron to organic molecule like lactate and ethanol.

Explanation of Solution
In the fermentation process in presence of pyruvate, the NAD+ is reinitiated from NADH by transferring electron to organic molecule like lactate and ethanol. To keep glycolysis continuing in the cell, it needs regenerated NAD+. There is no suitable way rather than the fermentation to produce NAD+. In glycolysis process in absence of regenerated NAD+ at energy generation step of glyceraldehyde 3-phosphate to 1, 3-biphosphoglycerate will not occur. The product glyceraldehydes 3-phosphate would accumulate in the cell unable to make either lactate or ethanol, neither it would able to regenerate NAD+. So, in this step also glycolysis process is blocked.
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Chapter 13 Solutions
ESSENTIAL CELL BIOLOGY (LL)-TEXT
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