Chapter 13, Problem 14SQ

a.

Summary Introduction

To define: Meconium ileus.

Concept introduction: Meconium is the substance that is present in intestine of the newly born baby. It forms the first stool of newborn baby. It contains succus entericus that is composed of bile acids, bile salts, and from the intestinal mucosa during intrauterine life.

b.

Summary Introduction

To describe: The effects of cystic fibrosis on the lungs and the liver.

Concept introduction: Cystic fibrosis (CF) is an inherited genetic disorder in children. It is also known as mucoviscidosis. In cystic fibrosis, various types of mutations occur to the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This gene has been recognized to relate to the proteins that are involved in chloride ion transport in the cell membrane. This defect of exocrine glands causes abnormal condensed mucus secretion. This mucus secretion is seen in case of primary cystic fibrosis.

c.

Summary Introduction

To explain: Several ways by which permanent damage can occur in the lungs and in the pancreas by cystic fibrosis.

Concept introduction: Cystic fibrosis (CF) is an inherited genetic disorder in children. It is also known as mucoviscidosis. In cystic fibrosis, various types of mutations occur to the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This gene has been recognized to relate to the proteins that are involved in chloride ion transport in the cell membrane. This defect of exocrine glands causes abnormal condensed mucus secretion. This mucus secretion is seen in case of primary cystic fibrosis.