A&P Bundle
11th Edition
ISBN: 9780134761404
Author: Martini
Publisher: PEARSON
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Chapter 12, Problem 23CP
Summary Introduction
To differentiate:
Between a neurotransmitter and a neuromodulator.
Introduction:
The human nervous system involves a complex chemical communication among its components. The chemicals can be neurotransmitters, neuromodulators or neuro-hormones. Some chemicals transmit the signal from one neuron to other while other chemicals modulate the activity of target cells.
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
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c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 12 Solutions
A&P Bundle
Ch. 12 - Describe the three anatomical divisions of the...Ch. 12 - Describe the two functional divisions of the...Ch. 12 - Identify the two components of the efferent...Ch. 12 - Prob. 4CPCh. 12 - Name the structural components of a typical...Ch. 12 - Classify neurons according to their structure.Ch. 12 - Classify neurons according to their function.Ch. 12 - Prob. 8CPCh. 12 - Prob. 9CPCh. 12 - Prob. 10CP
Ch. 12 - Prob. 11CPCh. 12 - Prob. 12CPCh. 12 - Prob. 13CPCh. 12 - What effect would decreasing the concentration of...Ch. 12 - Define action potential.Ch. 12 - Identify the steps involved in the generation and...Ch. 12 - Prob. 17CPCh. 12 - Which of the following axons is myelinated: one...Ch. 12 - Prob. 19CPCh. 12 - Prob. 20CPCh. 12 - What effect would blocking voltage-gated calcium...Ch. 12 - Prob. 22CPCh. 12 - Prob. 23CPCh. 12 - Prob. 24CPCh. 12 - Prob. 25CPCh. 12 - Prob. 26CPCh. 12 - Prob. 27CPCh. 12 - LEVEL 1 Reviewing Facts and Terms 1. Label the...Ch. 12 - Prob. 2RQCh. 12 - Prob. 3RQCh. 12 - Prob. 4RQCh. 12 - The neural cells responsible for the analysis of...Ch. 12 - Depolarization of a neuron plasma membrane will...Ch. 12 - Prob. 7RQCh. 12 - Receptors that bind acetylcholine at the...Ch. 12 - What are the major components of (a) the central...Ch. 12 - Prob. 10RQCh. 12 - Prob. 11RQCh. 12 - If the resting membrane potential of a neuron is...Ch. 12 - Prob. 13RQCh. 12 - What is the difference between anterograde flow...Ch. 12 - What is the functional difference among chemically...Ch. 12 - State the all-or-none principle cf action...Ch. 12 - Prob. 17RQCh. 12 - Prob. 18RQCh. 12 - What are the structural and functional differences...Ch. 12 - Describe the events that occur during nerve...Ch. 12 - Prob. 21RQCh. 12 - Prob. 22RQCh. 12 - Prob. 23RQCh. 12 - In multiple sclerosis, there is intermittent and...Ch. 12 - Prob. 25RQCh. 12 - Which cells of the CNS are targeted by the polio...Ch. 12 - Prob. 2CC
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