
Concept explainers
Muscle fibers possess the ability to contract and relax. Sarcomeres are the fundamental units of these muscle fibers that contain myosin protein. Cross-bridges are found where the heads of myosin dimer molecules overlap forming a bridge between thick and thin filaments of myofibrils.

Answer to Problem 1E
Correct answer:
The correct answer is option (c).
Explanation of Solution
Explanation/justification for the correct answer:
Contraction of muscle fibers is powered by ATP. Cross-bridge cycling is an important feature of consideration here. When myosin head attaches to actin cross-bridges are formed. The myosin continues to attach to ADP and inorganic phosphate (Pi) in a relaxed state. The release of Pi triggers pulling of actin and results in a power stroke of contraction. So, when the muscle cell is relaxed and intracellular ATP levels are normal, a cross-bridge will remain in the high energy form with ADP and Pi bound to it. So, the correct answer is option (c).
Explanation for the incorrect answer:
Option (a) states ‘bound to actin and in lower energy form.’ Cross-bridges are formed when myosin attaches to actin in a high energy form. So, this is an incorrect option.
Option (b) states ‘bound to actin and in higher energy form.’ Cross-bridges are formed when myosin attaches to actin in a high energy form. Cross-bridges are not directly bound to actin filaments. So, this is an incorrect answer.
Option (c) states ‘in high energy form with ATP bound to it.’ The high energy form of myosin is formed when it is attached to ADP and Pi, not ATP. Hence, this option is incorrect.
Option (d) states ‘in low energy form with nothing bound to it.’ Myosin filaments are bound to ADP and Pi in a high energy form when cross-bridges are formed in a relaxed state of muscle cells. So, this option is incorrect.
Among the given options, option (c) is the correct choice. When the muscle cell is relaxed and intracellular ATP levels are normal, a cross-bridge will remain in the high energy form with ADP and Pi bound to it.
Want to see more full solutions like this?
Chapter 12 Solutions
Principles of Human Physiology Plus Mastering A&P with Pearson eText - Access Card Package (6th Edition)
- Describe the principle of homeostasis.arrow_forwardExplain how the hormones of the glands listed below travel around the body to target organs and tissues : Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forwardWhat are the functions of the hormones produced in the glands listed below: Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forward
- Describe the hormones produced in the glands listed below: Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forwardPlease help me calculate drug dosage from the following information: Patient weight: 35 pounds, so 15.9 kilograms (got this by dividing 35 pounds by 2.2 kilograms) Drug dose: 0.05mg/kg Drug concentration: 2mg/mLarrow_forwardA 25-year-old woman presents to the emergency department with a 2-day history of fever, chills, severe headache, and confusion. She recently returned from a trip to sub-Saharan Africa, where she did not take malaria prophylaxis. On examination, she is febrile (39.8°C/103.6°F) and hypotensive. Laboratory studies reveal hemoglobin of 8.0 g/dL, platelet count of 50,000/μL, and evidence of hemoglobinuria. A peripheral blood smear shows ring forms and banana-shaped gametocytes. Which of the following Plasmodium species is most likely responsible for her severe symptoms? A. Plasmodium vivax B. Plasmodium ovale C. Plasmodium malariae D. Plasmodium falciparumarrow_forward
- please fill in missing parts , thank youarrow_forwardplease draw in the answers, thank youarrow_forwarda. On this first grid, assume that the DNA and RNA templates are read left to right. DNA DNA mRNA codon tRNA anticodon polypeptide _strand strand C с A T G A U G C A TRP b. Now do this AGAIN assuming that the DNA and RNA templates are read right to left. DNA DNA strand strand C mRNA codon tRNA anticodon polypeptide 0 A T G A U G с A TRParrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education





