Chapter 12, Problem 10P

Summary Introduction

To determine: The way in which mutation in ras which leads to the formation of a Ras protein with no GTPase activity affects a cell’s response to insulin.

Introduction:

Mutation is defined as a change in the sequence of genetic material which occurs either due to a mistake in replication or changes in the environment. DNA enzymes have a property of proof reading which prevents the mistake in a nucleotide sequence. But sometimes some mistakes are undetectable during DNA replication. These alterations in the nucleotide sequences are known as mutation.