Chapter 11.4, Problem 8ATS

Interpretation Introduction

Interpretation:

An efficient synthesis for given transformation has to be proposed.

  

Concept Introduction:

Soda amide (${\text{NaNH}}_{\text{2}}$): The strong base of ${\text{NaNH}}_{\text{2}}$ will deprotonate alkynes, alcohols and other organic functional groups with acidic protons such as esters and ketones.  It is also a very strong nucleophile.  It is a strong base and excellent nucleophile.

Elimination Reaction: It is the reaction in which the substituent from the given molecule is removed via $\text{E1}$ (the reaction depends only on the substrate involved in the reaction) or $\text{E2}$(the reaction depends on both of the substituents in the reaction) mechanism.