Fundamentals of Biostatistics
Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 11, Problem 95P

Diabetes

A group of 10-year-old boys were first ascertained in a camp for diabetic boys. They had their weight measured at baseline and again when they returned to camp 1 year later. Each time, a serum sample was obtained from which a determination of hemoglobin Ale (HgbAlc) was made. HgbAlc (also called glycosylated hemoglobin) is routinely used to monitor compliance with taking insulin injections. Usually, the poorer the compliance, the higher the HgbA1 c level will be. The hypothesis is that the level HgbAlc is related to weight. The data in Table 11.28 were obtained.

Compute a rank correlation between change in weight and change in HgbAlc, each over 1 year. Use this measure to directly test the hypothesis that change in weight over 1 year is related to change in HgbAlc. Report a two-tailed p-value, and provide a 95% confidence interval for the underlying rank correlation.

TABLE 11.28 Relationship between weight change and change In HgbAlc among diabetic boys

Chapter 11, Problem 95P, Diabetes A group of 10-year-old boys were first ascertained in a camp for diabetic boys. They had

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