VANDER'S HUMAN PHY W/ CONNECT & PROCT +
15th Edition
ISBN: 9781265160920
Author: WIDMAIER
Publisher: MCG
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Chapter 11, Problem 4PI
Summary Introduction
To list: The several ways by which the information flow between cells, tissues, and organs is an essential feature of homeostasis and allows for integration of physiological processes.
Introduction: Endocrine glands are those glands that secrete the hormone into the blood. Hormones are signaling molecules that act as chemical messengers in the body. They regulate the body processes by binding to their specific receptors.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 11 Solutions
VANDER'S HUMAN PHY W/ CONNECT & PROCT +
Ch. 11 - Prob. 1PICh. 11 - Prob. 2PICh. 11 - Prob. 3PICh. 11 - Prob. 4PICh. 11 - What distinguishes exocrine from endocrine...Ch. 11 - What are the three general chemical classes of...Ch. 11 - What are the major hormones produced by the...Ch. 11 - Which classes of hormones are carried in the blood...Ch. 11 - Do protein-bound hormones diffuse out of...Ch. 11 - Which organs are the major sites of hormone...
Ch. 11 - How do the rates of metabolism and excretion...Ch. 11 - Prob. A.8RQCh. 11 - Prob. A.9RQCh. 11 - Prob. A.10RQCh. 11 - Prob. A.11RQCh. 11 - Prob. A.12RQCh. 11 - Prob. A.13RQCh. 11 - Prob. A.14RQCh. 11 - Prob. A.15RQCh. 11 - Prob. 5PICh. 11 - Prob. B.1RQCh. 11 - Prob. B.2RQCh. 11 - Prob. B.3RQCh. 11 - Prob. B.4RQCh. 11 - Prob. B.5RQCh. 11 - Prob. B.6RQCh. 11 - Prob. 6PICh. 11 - Prob. C.1RQCh. 11 - Prob. C.2RQCh. 11 - Prob. C.3RQCh. 11 - Prob. C.4RQCh. 11 - Prob. 7PICh. 11 - Prob. D.1RQCh. 11 - Prob. D.2RQCh. 11 - Prob. D.3RQCh. 11 - Prob. D.4RQCh. 11 - Prob. D.5RQCh. 11 - Prob. 8PICh. 11 - Prob. E.1RQCh. 11 - Prob. E.2RQCh. 11 - Prob. E.3RQCh. 11 - Prob. E.4RQCh. 11 - Prob. E.5RQCh. 11 - Prob. E.6RQCh. 11 - Prob. E.7RQCh. 11 - Prob. E.8RQCh. 11 - Prob. E.9RQCh. 11 - Prob. E.10RQCh. 11 - Prob. 9PICh. 11 - Prob. 10PICh. 11 - Prob. F.1RQCh. 11 - Prob. F.2RQCh. 11 - Prob. F.3RQCh. 11 - Prob. F.4RQCh. 11 - Prob. 1RRCh. 11 - Prob. 2RRCh. 11 - Match the hormone with the function or feature...Ch. 11 - Prob. 2RCCh. 11 - Prob. 3RCCh. 11 - Prob. 4RCCh. 11 - Prob. 5RCCh. 11 - Prob. 6RCCh. 11 - Prob. 7RCCh. 11 - Prob. 8RCCh. 11 - Prob. 9RCCh. 11 - Prob. 10RCCh. 11 - Prob. 11RCCh. 11 - Prob. 12RCCh. 11 - Prob. 13RCCh. 11 - Prob. 14RCCh. 11 - Prob. 15RCCh. 11 - Prob. 1AAECh. 11 - Prob. 2AAECh. 11 - Prob. 3AAECh. 11 - Prob. 4AAECh. 11 - Prob. 5AAECh. 11 - Prob. 6AAECh. 11 - Prob. 7AAECh. 11 - A person with symptoms of hypothyroidism (i.e.,...Ch. 11 - Prob. 9AAECh. 11 - Prob. 10AAECh. 11 - Prob. 1GPACh. 11 - Prob. 2GPACh. 11 - Homeostasis is essential for health and survival....
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