Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
7th Edition
ISBN: 9781464126116
Author: David L. Nelson, Michael M. Cox
Publisher: W. H. Freeman
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Chapter 11, Problem 21P
Summary Introduction

To determine: The properties and mechanism of leucine transporter.

Introduction:

Leucine transporter is a type of transporter that helps to carry amino acids in and out of bacterial cells. It has a bundle of 12 α-helices that are able to form transport channel across the membrane.

Summary Introduction

To determine: Whether uptake of L-leucine is inhibited by ouabain.

Introduction:

Ouabain is a type of cardiac glycoside and its lower doses inhibit sodium-potassium ion pump in the body of organism Ouabain is a toxic chemical which is derived from plant and is used as poison in Africa for hunting.

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At a pH equal to the isoelectric point (pl) of alanine, the net charge of alanine is zero. Two structures can be drawn that have a net charge of zero, but the predominant form of alanine at its pl is zwitterionic. CH3 H,N CH3 ** H¸N-C H Zwitterionic H Uncharged OH Select statements that explain why alanine is predominantly zwitterionic at its pl. pk of alanine's amino group is more than its pl. pk of alanine's carboxyl group is more than its pl. PK of alanine's carboxyl group is less than its pl. pk of alanine's amino group is less than its pl. Correct Answer What fraction of alanine is in the completely uncharged form at its pl? 1 in 2.2 × 107 1 in 1.6 × 10² 1 in 4680 1 in 9460
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