Pathophysiology
Pathophysiology
6th Edition
ISBN: 9780323354813
Author: Jacquelyn L. Banasik PhD ARNP
Publisher: Saunders
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Chapter 11, Problem 1KQ
Summary Introduction

To describe: Based on the type of malignant transformation, find how the various types of lymphoma, leukemia, and plasma cell myelomas differ.

Introduction: The process through which the normal or benign tumor cells acquire the properties of cancer is termed as the malignant transformation. Thus, the changes or an alteration in which a normal cell undergoes when it becomes a cancerous cell is called malignant transformation.

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The lymphoma, leukemia, and plasma cell myeloma are the common neoplastic disorders of the lymphoid tissues and the bone marrow. Leukemia is a kind of malignant neoplasm of the immature stem cells. This is characterized by the diffusion and replacement of the bone marrow with the neoplastic blasts. The lymphoma is characterized by the malignancy of the cells of the lymphoid tissues including B cells, T cells, and natural killer cells. It usually arises in the lymph nodes. The plasma cell myeloma occurs due to the malignant transformation of mature B cells that secrete antibodies.

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