Chapter 10.8, Problem CQ

Interpretation Introduction

Interpretation:

The hydrogen atom on $\text{C-H}$ bond is moved with ${\text{NAD}}^{\text{+}}$ as one of the given option, has to be predicted.

Concept Introduction:

Oxidation of alcohols: Oxidation of primary alcohol gives an aldehyde or a carboxylic acid, depending on experimental conditions. Oxidation of secondary alcohol gives an ketone but not carboxylic acid on experimental conditions.

Oxidation of alcohols by$NA{D}^{+}$: Biological system does not use agents such as potassium dichromate or the oxide of other transition metals for the oxidation of alcohols to aldehyde or ketone or carboxylic acid. Instead biological system use ${\text{NAD}}^{\text{+}}$ that function as a biological oxidizing agent and reduced to $\text{NADH}$.

E2 reaction: In the reaction, a base abstract a proton, forcing the electrons to make a double bond and the leaving group leaves the substrate simultaneously.