
Microbiology Fundamentals: A Clinical Approach - Standalone book
2nd Edition
ISBN: 9780078021046
Author: Marjorie Kelly Cowan Professor, Jennifer Bunn
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
thumb_up100%
Chapter 10.2, Problem 5AYP
Explain the concept of selective toxicity.
Expert Solution & Answer

Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Which microbe does not live part of its lifecycle outside humans?
A. Toxoplasma gondii
B. Cytomegalovirus
C. Francisella tularensis
D. Plasmodium falciparum
explain your answer thoroughly.
Select all of the following that the ablation (knockout) or ectopoic expression (gain of function) of Hox can contribute to.
Another set of wings in the fruit fly, duplication of fingernails, ectopic ears in mice, excess feathers in duck/quail chimeras, and homeosis of segment 2 to jaw in Hox2a mutants
Select all of the following that changes in the MC1R gene can lead to:
Changes in spots/stripes in lizards, changes in coat coloration in mice, ectopic ear formation in Siberian hamsters, and red hair in humans
Chapter 10 Solutions
Microbiology Fundamentals: A Clinical Approach - Standalone book
Ch. 10.1 - State the main goal of antimicrobial treatment.Ch. 10.1 - Prob. 1NPCh. 10.1 - Identify the sources for the most commonly used...Ch. 10.1 - Describe two methods for testing antimicrobial...Ch. 10.1 - Prob. 4AYPCh. 10.2 - Explain the mode of action of penicillinases and...Ch. 10.2 - Identify two antimicrobials that act by inhibiting...Ch. 10.2 - Prob. 12AYPCh. 10.2 - Identify one example of a fluoroquinolone.Ch. 10.2 - Describe the mode of action of drugs that target...
Ch. 10.2 - Prob. 15AYPCh. 10.2 - Prob. 16AYPCh. 10.2 - Explain why antiprotozoal and antihelminthic drugs...Ch. 10.2 - List the three major targets of action of...Ch. 10.2 - Prob. 2NPCh. 10.2 - Explain the concept of selective toxicity.Ch. 10.2 - List the five major targets of antimicrobial...Ch. 10.2 - Prob. 7AYPCh. 10.2 - Distinguish between broad-spectrum and...Ch. 10.2 - Prob. 9AYPCh. 10.3 - Discuss two main ways that microbes acquire...Ch. 10.3 - Prob. 1MMCh. 10.3 - List five cellular or structural mechanisms that...Ch. 10.3 - Prob. 21AYPCh. 10.3 - Prob. 3NPCh. 10.4 - Distinguish between drug toxicity and allergic...Ch. 10.4 - Prob. 23AYPCh. 10.4 - Prob. 2MMCh. 10.4 - Prob. 4NPCh. 10.4 - Prob. 5NPCh. 10 - Can you think of a situation in which it would be...Ch. 10 - Prob. 1MCQCh. 10 - Prob. 1VCCh. 10 - Why does the penicillin group of antibiotics have...Ch. 10 - Prob. 2MCQCh. 10 - Prob. 3CTCh. 10 - Prob. 3MCQCh. 10 - Prob. 4CTCh. 10 - Microbial resistance to drugs is acquired through...Ch. 10 - Prob. 5CTCh. 10 - Treating malarial infections is theoretically...Ch. 10 - Prob. 6MCQCh. 10 - Prob. 7MCQCh. 10 - An antimicrobial drug with a _______ therapeutic...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Pleiotropic genes are genes that (blank) Cause a swapping of organs/structures, are the result of duplicated sets of chromosomes, never produce protein products, and have more than one purpose/functionarrow_forwardA loss of function mutation in Pitx1 enhancers can cause (blank) Removal of Pitx1 exons and growth of ectopic hindlimbs, growth of extra ectopic forelimbs, loss of forelimb specification and development, and loss of hindlimb specification and developmentarrow_forwardHox1a most likely contributes to (blank) patterning in the developing embryo? Ventral, posterior, limb or anteriorarrow_forward
- Select all of the following that can help establish Hox gene expression boundaries (things that affect Hox and not things that Hox affects). Retinoic acid, anterior/posterior axis, fibroblast growth factors, vagal neural crest, and enhancersarrow_forwardEctopic expression of Hox often results in (blank) phenotypes. (Blank) transformations are characterized by the replacement of one body part/structure with another. Hoxeotic, homealoneotic, joexotic, or homeoticarrow_forwardWhat's the difference when drawing omega-6 and omega-3?arrow_forward
- . Consider a base substitution mutation that occurred in a DNA sequence that resulted in a change in the encoded protein from the amino acid glutamic acid to aspartic acid. Normally the glutamic acid amino acid is located on the outside of the soluble protein but not near an active site. O-H¨ A. What type of mutation occurred? O-H B. What 2 types of chemical bonds are found in the R-groups of each amino acid? The R groups are shaded. CH2 CH2 CH2 H2N-C-COOH H2N-C-COOH 1 H Glutamic acid H Aspartic acid C. What 2 types of bonds could each R-group of each of these amino acids form with other molecules? D. Consider the chemical properties of the two amino acids and the location of the amino acid in the protein. Explain what effect this mutation will have on this protein's function and why.arrow_forwardengineered constructs that consist of hollow fibers are acting as synthetic capillaries, around which cells have been loaded. The cellular space around a single fiber can be modeled as if it were a Krogh tissue cylinder. Each fiber has an outside “capillary” radius of 100 µm and the “tissue” radius can be taken as 200 µm. The following values apply to the device:R0 = 20 µM/secaO2 = 1.35 µM/mmHgDO2,T = 1.67 x 10-5 cm2/secPO2,m = 4 x 10-3 cm/secInstead of blood inside the fibers, the oxygen transport and tissue consumption are being investigated by usingan aqueous solution saturated with pure oxygen. As a result, there is no mass transfer resistance in the synthetic“capillary”, only that due to the membrane itself. Rather than accounting for pO2 variations along the length ofthe fiber, use an average value in the “capillary” of 130 mmHg.Is the tissue fully oxygenated?arrow_forwardMolecular Biology Please help with question. thank you You are studying the expression of the lac operon. You have isolated mutants as described below. In the presence of glucose, explain/describe what would happen, for each mutant, to the expression of the lac operon when you add lactose AND what would happen when the bacteria has used up all of the lactose (if the mutant is able to use lactose).5. Mutations in the lac operator that strengthen the binding of the lac repressor 200 fold 6. Mutations in the promoter that prevent binding of RNA polymerase 7. Mutations in CRP/CAP protein that prevent binding of cAMP8. Mutations in sigma factor that prevent binding of sigma to core RNA polymerasearrow_forward
- Molecular Biology Please help and there is an attached image. Thank you. A bacteria has a gene whose protein/enzyme product is involved with the synthesis of a lipid necessary for the synthesis of the cell membrane. Expression of this gene requires the binding of a protein (called ACT) to a control sequence (called INC) next to the promoter. A. Is the expression/regulation of this gene an example of induction or repression?Please explain:B. Is this expression/regulation an example of positive or negative control?C. When the lipid is supplied in the media, the expression of the enzyme is turned off.Describe one likely mechanism for how this “turn off” is accomplished.arrow_forwardMolecular Biology Please help. Thank you. Discuss/define the following:(a) poly A polymerase (b) trans-splicing (c) operonarrow_forwardMolecular Biology Please help with question. Thank you in advance. Discuss, compare and contrast the structure of promoters inprokaryotes and eukaryotes.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Essentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:CengageBasic Clinical Lab Competencies for Respiratory C...NursingISBN:9781285244662Author:WhitePublisher:Cengage
Essentials of Pharmacology for Health Professions
Nursing
ISBN:9781305441620
Author:WOODROW
Publisher:Cengage
Basic Clinical Lab Competencies for Respiratory C...
Nursing
ISBN:9781285244662
Author:White
Publisher:Cengage
Drug Abuse, Causes, Signs and Symptoms, Diagnosis and Treatment.; Author: Medical Centric;https://www.youtube.com/watch?v=b6Dte96WdqM;License: Standard youtube license