EBK ESSENTIALS OF BIOLOGY
EBK ESSENTIALS OF BIOLOGY
4th Edition
ISBN: 9780100237209
Author: Mader
Publisher: YUZU
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Chapter 10, Problem S15.2CTC
Summary Introduction

To determine:

The process of how natural selection may favour heterozygote, as is the case with sickle cell disease.

Given:

Natural selection may favour heterozygote, as is the case with sickle cell disease.

Introduction:

Sickle cell disease is a major health concern mainly in tropic countries and it is due to a mutation of the gene coding for the β-globin. The mutated allele is HbS and the wild type is HbA. It is a recessive gene disease the mutation in homozygous recessive condition leads to sickle cell disease. The natural selection is of different forms namely the directional selection, stabilizing selection and the disruptive selection.

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What is Genomics - Full Length; Author: Genome BC;https://www.youtube.com/watch?v=mmgIClg0Y1k;License: Standard youtube license