Chemistry: The Central Science Plus Mastering Chemistry with Pearson eText -- Access Card Package (14th Edition)
14th Edition
ISBN: 9780134292816
Author: Theodore E. Brown, H. Eugene LeMay, Bruce E. Bursten, Matthew E. Stoltzfus
Publisher: PEARSON
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Chapter 10, Problem 96E
Interpretation Introduction
To determine: If the radius calculated from van der Waals constant
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Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
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Chapter 10 Solutions
Chemistry: The Central Science Plus Mastering Chemistry with Pearson eText -- Access Card Package (14th Edition)
Ch. 10.2 - Prob. 10.1.1PECh. 10.2 -
Gallium melts just above room temperature...Ch. 10.2 - Prob. 10.2.1PECh. 10.2 - Prob. 10.2.2PECh. 10.3 - Prob. 10.3.1PECh. 10.3 - Prob. 10.3.2PECh. 10.4 - Prob. 10.4.1PECh. 10.4 - Prob. 10.4.2PECh. 10.4 - Prob. 10.5.1PECh. 10.4 - Prob. 10.5.2PE
Ch. 10.4 - Prob. 10.6.1PECh. 10.4 - Prob. 10.6.2PECh. 10.5 - Prob. 10.7.1PECh. 10.5 - Prob. 10.7.2PECh. 10.5 - Prob. 10.8.1PECh. 10.5 - Prob. 10.8.2PECh. 10.5 - Prob. 10.9.1PECh. 10.5 - Prob. 10.9.2PECh. 10.6 - Prob. 10.10.1PECh. 10.6 - Prob. 10.10.2PECh. 10.6 - Prob. 10.11.1PECh. 10.6 - Prob. 10.11.2PECh. 10.7 - Prob. 10.12.1PECh. 10.7 - Prob. 10.12.2PECh. 10.8 - Fill in the blanks for the following statement:...Ch. 10.8 - Prob. 10.13.2PECh. 10.8 - Prob. 10.14.1PECh. 10.8 - Prob. 10.14.2PECh. 10.9 - Calculate the pressure of a 2975-mol sample of N2...Ch. 10.9 - Prob. 10.15.2PECh. 10 - Prob. 1DECh. 10 - Prob. 1ECh. 10 - Prob. 2ECh. 10 - Consider the sample of gas depicted here_ What...Ch. 10 - Imagine that the reaction 2CO(g)+O2(g)2CO(g)...Ch. 10 - Suppose you have a fixed amount of an ideal gas at...Ch. 10 - Prob. 6ECh. 10 - Prob. 7ECh. 10 - Prob. 8ECh. 10 - Prob. 9ECh. 10 - Prob. 10ECh. 10 -
10.11 A thin glass tube 1 m long is filled with...Ch. 10 -
10.12 The graph below shows the change in...Ch. 10 - Prob. 13ECh. 10 - Prob. 14ECh. 10 - Prob. 15ECh. 10 - Prob. 16ECh. 10 - Prob. 17ECh. 10 - a. The compound 1-iodododecane is a nonvolatile...Ch. 10 - Prob. 19ECh. 10 - Prob. 20ECh. 10 - Prob. 21ECh. 10 - Prob. 22ECh. 10 - Prob. 23ECh. 10 - Prob. 24ECh. 10 - You have a gas at 25C confined to a cylinder with...Ch. 10 - Prob. 26ECh. 10 - Prob. 27ECh. 10 - Nitrogen and hydrogen gases react to form ammonia...Ch. 10 -
10.29
a. What conditions are represented by the...Ch. 10 - Prob. 30ECh. 10 - Prob. 31ECh. 10 - Prob. 32ECh. 10 - Prob. 33ECh. 10 - Prob. 34ECh. 10 - Prob. 35ECh. 10 - Prob. 36ECh. 10 - Calculate the number of molecules in deep breath...Ch. 10 - If the pressure exerted by ozone, O3, in the...Ch. 10 - A scuba diver’s tank contain 0.29 kg of O2...Ch. 10 - Prob. 40ECh. 10 - Prob. 41ECh. 10 - Prob. 42ECh. 10 - Chlorine is widely used to purify municipal water...Ch. 10 - Many gases are shipped in high-pressure...Ch. 10 - Prob. 45ECh. 10 - Prob. 46ECh. 10 - Rank the following gases from least to denser at...Ch. 10 - Prob. 48ECh. 10 - Prob. 49ECh. 10 - Prob. 50ECh. 10 - Prob. 51ECh. 10 - Prob. 52ECh. 10 - Prob. 53ECh. 10 - Prob. 54ECh. 10 - Magnesium can be used as a ‘getter” in evacuated...Ch. 10 - Prob. 56ECh. 10 - The metabolic oxidation of glucose, C6H12O6, in...Ch. 10 - Prob. 58ECh. 10 - Prob. 59ECh. 10 - Prob. 60ECh. 10 - Consider the apparatus shown in the following...Ch. 10 - Prob. 62ECh. 10 - A mixture containing 0.75 mol He(g), 0.330 mol...Ch. 10 - A deep-sea diver uses a gas cylinder with a volume...Ch. 10 - Prob. 65ECh. 10 - Prob. 66ECh. 10 - Prob. 67ECh. 10 - Prob. 68ECh. 10 - Prob. 69ECh. 10 - Prob. 70ECh. 10 - Prob. 71ECh. 10 - Prob. 72ECh. 10 - Prob. 73ECh. 10 - Prob. 74ECh. 10 - Prob. 75ECh. 10 - Indicate which of the following statement...Ch. 10 - Prob. 77ECh. 10 - Prob. 78ECh. 10 - Prob. 79ECh. 10 - Suppose you have two 1-L flasks, one containing N2...Ch. 10 - Prob. 81ECh. 10 -
10.8
Place the following gases in order of...Ch. 10 - Prob. 83ECh. 10 - Prob. 84ECh. 10 - Prob. 85ECh. 10 - Prob. 86ECh. 10 - Prob. 87ECh. 10 - Prob. 88ECh. 10 - Prob. 89ECh. 10 - Prob. 90ECh. 10 - Prob. 91ECh. 10 - Prob. 92ECh. 10 - Prob. 93ECh. 10 - Prob. 94ECh. 10 - Prob. 95ECh. 10 - Prob. 96ECh. 10 - Prob. 97AECh. 10 - A gas bubble with a volume of 1.0 mm3 originates...Ch. 10 - A 15.0-L tank is filled with helium gas at a...Ch. 10 - Prob. 100AECh. 10 - Prob. 101AECh. 10 - Prob. 102AECh. 10 - Prob. 103AECh. 10 - Prob. 104AECh. 10 - Prob. 105AECh. 10 - Prob. 106AECh. 10 - Prob. 107AECh. 10 - Prob. 108AECh. 10 - Prob. 109AECh. 10 - The density of gas of unknown molar mass was...Ch. 10 - A glass vessel fitted with a stopcock valve has a...Ch. 10 - Prob. 112AECh. 10 -
10.113 consider the following gases. All at STP:...Ch. 10 - Prob. 114AECh. 10 - Prob. 115AECh. 10 - Prob. 116AECh. 10 - Prob. 117AECh. 10 - Prob. 118IECh. 10 - Prob. 119IECh. 10 - Prob. 120IECh. 10 -
10.121 A 4.00-g sample of a mixture of CaO and...Ch. 10 - Prob. 122IECh. 10 - Prob. 123IECh. 10 - Chlorine dioxide gas (CIO2) is used as a...Ch. 10 - Natural gas is very abundant in many Middle...Ch. 10 - Prob. 126IECh. 10 - Prob. 127IE
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