The detailed mechanism for the given reaction is to be drawn. Concept introduction: The α carbon (carbon adjacent to the carbonyl carbon) having at least one hydrogen atom can be converted to a nucleophile by deprotonation. Thus, substitution at α carbon of an aldehyde or ketones is possible. The reaction of primary alkyl halides proceeds via S N 2 mechanism. The good and less sterically hindered nucleophile favors S N 2 mechanism. The substrate having both nucleophile as well as a leaving group undergoes intramolecular nucleophilic substitution reaction and results in a cyclic product.

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Chapter 10, Problem 10.39P

Interpretation Introduction

Interpretation:

The detailed mechanism for the given reaction is to be drawn.

Concept introduction:

The α carbon (carbon adjacent to the carbonyl carbon) having at least one hydrogen atom can be converted to a nucleophile by deprotonation. Thus, substitution at α carbon of an aldehyde or ketones is possible. The reaction of primary alkyl halides proceeds via SN2 mechanism. The good and less sterically hindered nucleophile favors SN2 mechanism. The substrate having both nucleophile as well as a leaving group undergoes intramolecular nucleophilic substitution reaction and results in a cyclic product.

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Answer 2

Question

Chapter 10, Problem 10.39P

Interpretation Introduction

Interpretation:

The detailed mechanism for the given reaction is to be drawn.

Concept introduction:

The α carbon (carbon adjacent to the carbonyl carbon) having at least one hydrogen atom can be converted to a nucleophile by deprotonation. Thus, substitution at α carbon of an aldehyde or ketones is possible. The reaction of primary alkyl halides proceeds via SN2 mechanism. The good and less sterically hindered nucleophile favors SN2 mechanism. The substrate having both nucleophile as well as a leaving group undergoes intramolecular nucleophilic substitution reaction and results in a cyclic product.

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Answer 3

Question

Chapter 10, Problem 10.39P

Interpretation Introduction

Interpretation:

The detailed mechanism for the given reaction is to be drawn.

Concept introduction:

The α carbon (carbon adjacent to the carbonyl carbon) having at least one hydrogen atom can be converted to a nucleophile by deprotonation. Thus, substitution at α carbon of an aldehyde or ketones is possible. The reaction of primary alkyl halides proceeds via SN2 mechanism. The good and less sterically hindered nucleophile favors SN2 mechanism. The substrate having both nucleophile as well as a leaving group undergoes intramolecular nucleophilic substitution reaction and results in a cyclic product.

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Answer 4

Question

Chapter 10, Problem 10.39P

Interpretation Introduction

Interpretation:

The detailed mechanism for the given reaction is to be drawn.

Concept introduction:

The α carbon (carbon adjacent to the carbonyl carbon) having at least one hydrogen atom can be converted to a nucleophile by deprotonation. Thus, substitution at α carbon of an aldehyde or ketones is possible. The reaction of primary alkyl halides proceeds via SN2 mechanism. The good and less sterically hindered nucleophile favors SN2 mechanism. The substrate having both nucleophile as well as a leaving group undergoes intramolecular nucleophilic substitution reaction and results in a cyclic product.

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Answer 5

Chapter 10, Problem 10.39P

Interpretation Introduction

Interpretation:

The detailed mechanism for the given reaction is to be drawn.

Concept introduction:

The α carbon (carbon adjacent to the carbonyl carbon) having at least one hydrogen atom can be converted to a nucleophile by deprotonation. Thus, substitution at α carbon of an aldehyde or ketones is possible. The reaction of primary alkyl halides proceeds via SN2 mechanism. The good and less sterically hindered nucleophile favors SN2 mechanism. The substrate having both nucleophile as well as a leaving group undergoes intramolecular nucleophilic substitution reaction and results in a cyclic product.

Answer 6

Chapter 10, Problem 10.39P

Interpretation Introduction

Interpretation:

The detailed mechanism for the given reaction is to be drawn.

Concept introduction:

The α carbon (carbon adjacent to the carbonyl carbon) having at least one hydrogen atom can be converted to a nucleophile by deprotonation. Thus, substitution at α carbon of an aldehyde or ketones is possible. The reaction of primary alkyl halides proceeds via SN2 mechanism. The good and less sterically hindered nucleophile favors SN2 mechanism. The substrate having both nucleophile as well as a leaving group undergoes intramolecular nucleophilic substitution reaction and results in a cyclic product.

Answer 7

Chapter 10, Problem 10.39P

Interpretation Introduction

Interpretation:

The detailed mechanism for the given reaction is to be drawn.

Concept introduction:

The α carbon (carbon adjacent to the carbonyl carbon) having at least one hydrogen atom can be converted to a nucleophile by deprotonation. Thus, substitution at α carbon of an aldehyde or ketones is possible. The reaction of primary alkyl halides proceeds via SN2 mechanism. The good and less sterically hindered nucleophile favors SN2 mechanism. The substrate having both nucleophile as well as a leaving group undergoes intramolecular nucleophilic substitution reaction and results in a cyclic product.

Answer 8

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Answer 11

Ch. 10 - Prob. 10.1P Ch. 10 - Prob. 10.2P Ch. 10 - Prob. 10.3P Ch. 10 - Prob. 10.4P Ch. 10 - Prob. 10.5P Ch. 10 - Prob. 10.6P Ch. 10 - Prob. 10.7P Ch. 10 - Prob. 10.8P Ch. 10 - Prob. 10.9P Ch. 10 - Prob. 10.10P

Solution Summary: The author explains the mechanism of the nucleophilic substitution reaction, which involves the deprotonation of a carbonyl carbon and the formation of an enolate anion.

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