How the people (who left the city) have minor cases of yellow fever or evaded the infection completely and the first frost brought an end to the yellow fever outbreak. Case summary: In the given scenario, peoples of Philadelphia (US) were severely affected by yellow fever. Initially, the yellow fever virus was carried by the refuges of Haiti; later, they were escaped to Philadelphia. The yellow fever virus was spread to other healthy Philadelphians by a mosquito bite ( Aedes aegypti ). An epidemic of yellow fever outbreak was begun in 1793, which kills about 10% of population in the city. Within three months, about 30% of the population shifted to other places for safer lives.

Question

The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.

Answer 1

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Chapter 1, Problem 1CCS

(1)

Summary Introduction

To determine:

How the people (who left the city) have minor cases of yellow fever or evaded the infection completely and the first frost brought an end to the yellow fever outbreak.

Case summary:

In the given scenario, peoples of Philadelphia (US) were severely affected by yellow fever. Initially, the yellow fever virus was carried by the refuges of Haiti; later, they were escaped to Philadelphia. The yellow fever virus was spread to other healthy Philadelphians by a mosquito bite (Aedes aegypti). An epidemic of yellow fever outbreak was begun in 1793, which kills about 10% of population in the city. Within three months, about 30% of the population shifted to other places for safer lives.

(2)

Summary Introduction

To determine:

The first frost brought an end to the yellow fever outbreak.

Case summary:

In the given scenario, people of Philadelphia (US) were severely affected by yellow fever. Initially, the yellow fever virus was carried by the refuges of Haiti; later, they escaped to Philadelphia. The yellow fever virus was spread to other healthy Philadelphians by mosquito bite (Aedes aegypti). An epidemic of yellow fever outbreak was begun in 1793, which kills about 10% of population in the city. Within three months, about 30% of the population shifted to other places for safer lives.

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