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You identify a disease of epidermal cells in mice in which Gene A is not expressed. Further analyses reveals that the sequence of Gene A in affected and normal mice is the SAME. Which of the choices below could explain why Gene A is NOT expressed in the epidermal cells of the affected mice. Select all that apply. A. Lysine residues are acetylated in Histone tails close to Gene A in affected mice. B. Tyrosine residues are phosphorylated in Histone tails close to Gene A in affected mice. C. Epidermal cells of affected mice lack the transcription factors associated with Gene A. D. DNA in the promoter region of Gene A of affected mice is methylated.

You identify a disease of epidermal cells in mice in which Gene A is not expressed. Further analyses reveals that the sequence of Gene A in affected and normal mice is the SAME. Which of the choices below could explain why Gene A is NOT expressed in the epidermal cells of the affected mice. Select all that apply. A. Lysine residues are acetylated in Histone tails close to Gene A in affected mice. B. Tyrosine residues are phosphorylated in Histone tails close to Gene A in affected mice. C. Epidermal cells of affected mice lack the transcription factors associated with Gene A. D. DNA in the promoter region of Gene A of affected mice is methylated.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION You identify a disease of epidermal cells in mice in which Gene A is not expressed. Further analyses reveals that the sequence of Gene A in affected and normal mice is the SAME. Which of the choices below could explain why Gene A is NOT expressed in the epidermal cells of the affected mice. Select all that apply. A. Lysine residues are acetylated in Histone tails close to Gene A in affected mice. B. Tyrosine residues are phosphorylated in Histone tails close to Gene A in affected mice. C. Epidermal cells of affected mice lack the transcription factors associated with Gene A. D. DNA in the promoter region of Gene A of affected mice is methylated.
Transcribed Image Text:QUESTION You identify a disease of epidermal cells in mice in which Gene A is not expressed. Further analyses reveals that the sequence of Gene A in affected and normal mice is the SAME. Which of the choices below could explain why Gene A is NOT expressed in the epidermal cells of the affected mice. Select all that apply. A. Lysine residues are acetylated in Histone tails close to Gene A in affected mice. B. Tyrosine residues are phosphorylated in Histone tails close to Gene A in affected mice. C. Epidermal cells of affected mice lack the transcription factors associated with Gene A. D. DNA in the promoter region of Gene A of affected mice is methylated.
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