You have several mutant strains of virions. Describe the replication cycle and outcome for each mutant vir compared to the WT of the virus. 1. M1: Measles virus that does not package the viral transcriptase in the virion. 2. M2: Adenovirus that does not encode for a DNA Pol 3. M3: Influenza virus encodes for a PB2 protein that cannot cleave the 5'cap of host mRNA. 4. M4: HIV that does not encode for a function protease protein. 5. Poliovirus with a mutation in the RdRp gene which makes it non-functional 6. HBV that does not encode for a functional X protein

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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You have several mutant strains of virions. Describe the replication cycle and outcome for each mutant virus
compared to the WT of the virus.
1. M1: Measles virus that does not package the viral transcriptase in the virion.
2. M2: Adenovirus that does not encode for a DNA Pol
3. M3: Influenza virus encodes for a PB2 protein that cannot cleave the 5'cap of host mRNA.
4. M4: HIV that does not encode for a function protease protein.
5. Poliovirus with a mutation in the RdRp gene which makes it non-functional
6. HBV that does not encode for a functional X protein.
Transcribed Image Text:You have several mutant strains of virions. Describe the replication cycle and outcome for each mutant virus compared to the WT of the virus. 1. M1: Measles virus that does not package the viral transcriptase in the virion. 2. M2: Adenovirus that does not encode for a DNA Pol 3. M3: Influenza virus encodes for a PB2 protein that cannot cleave the 5'cap of host mRNA. 4. M4: HIV that does not encode for a function protease protein. 5. Poliovirus with a mutation in the RdRp gene which makes it non-functional 6. HBV that does not encode for a functional X protein.
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