You have 1200 base-pairs coding sequences. When aligning them, you observe an average of 8 synonymous and 8 nonsynonymous substitutions. Assuming approximately 25% synonymous sites and 75% nonsynonymous sites, which of the following statements is TRUE?

Database System Concepts
7th Edition
ISBN:9780078022159
Author:Abraham Silberschatz Professor, Henry F. Korth, S. Sudarshan
Publisher:Abraham Silberschatz Professor, Henry F. Korth, S. Sudarshan
Chapter1: Introduction
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You have 1200 base-pairs coding sequences. When aligning them, you
observe an average of 8 synonymous and 8 nonsynonymous substitutions.
Assuming approximately 25% synonymous sites and 75% nonsynonymous
sites, which of the following statements is TRUE?
The number of synonymous sites is S = 1200 x 3 x 25% = 900
Since 8/8=1, the polymorphism at the locus is evolving following neutral
evolution
Dn/Ds less than one rejects the neutral theory
Dn/Ds higher than one is predicted by the neutral theory as a common
observation
None of the above
Transcribed Image Text:You have 1200 base-pairs coding sequences. When aligning them, you observe an average of 8 synonymous and 8 nonsynonymous substitutions. Assuming approximately 25% synonymous sites and 75% nonsynonymous sites, which of the following statements is TRUE? The number of synonymous sites is S = 1200 x 3 x 25% = 900 Since 8/8=1, the polymorphism at the locus is evolving following neutral evolution Dn/Ds less than one rejects the neutral theory Dn/Ds higher than one is predicted by the neutral theory as a common observation None of the above
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