You are presented with the following clinical scenario: "A 50 year old patient presents with fatigue, night sweats and weight loss. Flow cytometry shows increased numbers of immature leukocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis Chronic leukaemia O Sepsis Chronic Myelomonocytic Leukaemia Severe Combined Immunodeficiency

You are presented with the following clinical scenario: "A 50 year old patient presents with fatigue, night sweats and weight loss. Flow cytometry shows increased numbers of immature leukocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis Chronic leukaemia O Sepsis Chronic Myelomonocytic Leukaemia Severe Combined Immunodeficiency

An Illustrated Guide To Vet Med Term

4th Edition

ISBN:9781305465763

Author:ROMICH

Publisher:ROMICH

Chapter15: Feed And Protect Me

Section: Chapter Questions

Problem 1CP

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You are presented with the following clinical scenario: "A 12 month old male child presents with recurrent bacterial infections. Flow cytometry shows a complete lack of B- lymphocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis O HIV/AIDS O COVID-19 O LAD type 1 U E CD4-FITC CD8-PE CD45-PE CD8-PE 70% 13% 52% 10% 82% 5% 27% 5% CD8-PE CD4-FITC CD20-FITC CD4-FITC 17% 38% 13% 68% Agammaglobulinaemia CD45-PE CD4-FITC CD45-PE CD45-PE 35% 3% 62% 8% 93% 22% CD15-FITC CD8-PE CD20-FITC CD15-FITC Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample 62% 30% 0% 77%
BACKGROUND A 2-year-old black girl is being seen by the hematologist after her pediatrician found her to be severely anemic with splenomegaly and jaundice. Her mother gives a possible history of a “blood problem” in her family but doesn’t know for sure. Her hemoglobin electrophoresis was normal, and the complete blood count (CBC) revealed a normocytic anemia. The platelet and white blood cell counts are normal. On the peripheral smear, there are many bizarre erythrocytes, including spiculated cells. A diagnosis of pyruvate kinase deficiency is made. Pyruvate kinase deficiency (PKD) can be inherited in an autosomal recessive manner, which means that a child must inherit a gene with the disease-causing mutation from both parents in order for the disorder to be inherited. The PLKR gene regulates the synthesis of the pyruvate kinase enzyme, which is located in the liver and red blood cells. Pyruvate kinase deficiency (PKD) is a rare genetic disorder characterized by the premature…
A 27‐year‐old woman presents to her general practitioner with fatigue and easy bruising. A full blood count shows pancytopenia, and she is admitted to the hospital. The partial thromboplastin and prothrombin time (international normalized ratio) are both abnormal, and fragmented red cells are noted on blood film. Which ONE of the following is the most likely diagnosis in this case? Select one: A.Acute lymphoblastic leukaemia B.Acute promyelocytic leukaemia C.Acute myeloid leukaemia without differentiation D.Acute monoblastic leukaemia
A male college freshman is seen at the college health service complaining of general fatigue, a sore throat, and swollen lymph nodes in his neck. A throat culture is done, and blood is drawn for hematology studies and a rapid MonoSlide test. Hematology results show a normal hemoglobin value and a slight increase in the white cell count, with many large, reactive lymphocytes seen in the differential. A rapid strep test is negative, but a second swab is cultured on sheep blood and incubated, with the result to be read in 18 hours. Result from the MonoSlide test is positive. Questions What laboratory tests could exclude or include the possible diagnoses? Why did the patient have an increased white blood count with abnormal appearing lymphocytes?
Please explain, would the answer be C). This patient is at risk for infection because of his low white blood cell count. 64-year-old African American male visits his primary care physician with complaints of bone pain, fatigue, nausea, loss of appetite, and constipation. The patient has a history of good health and exercises regularly. However, his recent symptoms have started to interfere with his active lifestyle. After a physical examination, his physician orders laboratory analysis to identify what might be causing his symptoms. Based on the CBC results and your knowledge of the cellular components of the immune system, what is an immunological concern for this patient? A). This patient is at increased risk for bruising and bleeding because of his low platelet count. B). The patient’s fatigue is caused by the lack of red blood cells (anemia). C). This patient is at risk for infection because of his low white blood cell count.
Case scenario A 19-year-old male visits his primary care physician with a sore throat, swollen lymph nodes, and extreme fatigue. During the visit, the nurse finds that he has a fever. The patient reports that he is attending his second year of college at a local university. The physician performs a physical examination, which confirms large, swollen, painful lymph nodes. He decides to send the patient to the office laboratory for blood work. He orders a complete blood count (CBC) and viral and bacterial studies. Question: 1. Based on the information obtained thus far, what does the laboratory analysis indicate? Explain your answer. 2. The patient's symptoms of fever and painful, swollen lymph nodes are caused by what innate immune mechanisms? Explain your answer 3. About 50% of patients with chronic viral infection develop splenomegaly. Based on what you know about the organs of the immune system, why would this condition develop?
Answer the questions below in details on “ Absolute cell counts using a Neubauer haemocytometer ( white blood cell count, red blood cell count and platelet count) “ 1)What is this test? 2)How is it carried out/what are the key aspects of the technique needed for accuracy? 3)What can it tell us? 4)What are the sources of error that could impact your data and interpretation?
A laboratory scientist working in the hematology department receives a patient sample for a CBC. The scientist checks the sample for clots and mixes the tube well. They place the tube on the instruments and await the results. The results indicate that there are elevated numbers of white blood cells, with a large majority of lymphocytes. This resulted in the addition of a differential examination. The lab scientist then prepares a stained peripheral push smear for differential review. Once dry, the slide is placed on the microscope for review. When scanning with 10x objective, the lab scientist finds the feathered edge and changes to an objective with higher magnification. On higher magnification the lab scientist has difficulty finding a clear view. The view is foggy and lacks resolution. When the scientist checks the sample of clots and mixes the tube before testing, they are checking for what kind of variable that could have an effect on testing? The laboratory scientist…
> Thrombocytopenia | NHLBI, NIH diagnosis and treatment of disea x V Thrombocytopenia (low platelet x re.com/courses/11055/assignments/285768 Maps A Get FREE Delivery!u.. Submitting a text entry box, a website url, a media recording, or a file upload A Case Study On Mononucleosis Mononucleosis is an infection caused by the Epstein-Barr virus, often called the "kissing disease." It is usually seen in teens and young adults but anyone of any age can contract the virus. There is research but it is limited because mono is not a disease that must be reported to agencies during outbreaks. Instructions 1. For this assignment, visit our Virtual Library or other reliable sources and find a recent article or case study about a mono outbreak. 2. Write a short essay in which you: o summarize the outbreak, o describe the process of diagnosis, and o provide details about the therapy given to infected individuals. 3. Make sure to cite the references used in your case study or article. Note: Please…
A 41-year-old man presents to the emergency department complaining of fever, chills, and malaise. A preliminary diagnosis of infective endocarditis is established, and he is started on an intravenous antibiotic administered every 6 hours. The antibiotic follows first-order kinetics and has a volume of distribution of 80 L and a clearance of 1 L/min. How much should be administered every 6 hours to maintain a therapeutic steady-state plasma concentration of 8 mg/L? A. 84 mg B. 126 mg C.1300 mg D. 1720 mg E. 2880 mg
Using function as the discriminating feature, draw up a dichotomous key to distinguish the 4 cells listed. Eosinophil lymphocyte neutrophil monocyte
When a patient exhibits a four-fold or greater rise in antibody titer against a specific microbial antigen between acute-phase and convalescent-phase serum samples, this is considered to be a "seroconversion". Which of the following would be a correct interpretation of a seroconversion? None of the other four answers are a correct interpretation of a seroconversion These findings cannot be interpreted because antibodies aren't specific enough for antigens There is no evidence of current active infection because that would require that the antibody titer is decreasing rather than increasing These results show that the microbe itself has been detected in the patient's sample(s) The results show evidence of current or recent infection by the specific microbe because there has been an active immunologic response to its antigen