Homework Help is Here – Start Your Trial Now!
Science
Biology
You are analyzing the DHPS gene and protein. DHPS catalyzes the first committed step in Folic Acid production, which is an essential precursor for nucleotide synthesis. DHPS is the target of the antibiotic sulfonamide, which blocks DHPS catalytic activity by acting as a competitive inhibitor. You also have mutant version of DHPS (called DHPS-R) that provides resistance to sulfonamides because it has much lower binding affinity to the antibiotic. Which statement do you anticipate to be true? Refer to the original DHSP gene version as DHSP-S. DHPS-R is a better enzyme overall than DHPS-S DHPS-R is more fit than DHPS-S in the absence of antibiotics DHPS-S is more fit in the presence of antibiotics than DHPS-R DHPS-S has a higher affinity for its normal substrates than DHPS-R DHPS-R likely has a nonsense or frameshift mutation

You are analyzing the DHPS gene and protein. DHPS catalyzes the first committed step in Folic Acid production, which is an essential precursor for nucleotide synthesis. DHPS is the target of the antibiotic sulfonamide, which blocks DHPS catalytic activity by acting as a competitive inhibitor. You also have mutant version of DHPS (called DHPS-R) that provides resistance to sulfonamides because it has much lower binding affinity to the antibiotic. Which statement do you anticipate to be true? Refer to the original DHSP gene version as DHSP-S. DHPS-R is a better enzyme overall than DHPS-S DHPS-R is more fit than DHPS-S in the absence of antibiotics DHPS-S is more fit in the presence of antibiotics than DHPS-R DHPS-S has a higher affinity for its normal substrates than DHPS-R DHPS-R likely has a nonsense or frameshift mutation

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question

Answer question 29

You are analyzing the DHPS gene and protein. DHPS catalyzes the first committed step in Folic Acid production, which is an essential precursor for nucleotide synthesis. DHPS is the target of the antibiotic sulfonamide, which blocks DHPS catalytic activity by acting as a competitive inhibitor. You also have mutant version of DHPS (called DHPS-R) that provides resistance to sulfonamides because it has much lower binding affinity to the antibiotic. Which statement do you anticipate to be true? Refer to the original DHSP gene version as DHSP-S. DHPS-R is a better enzyme overall than DHPS-S DHPS-R is more fit than DHPS-S in the absence of antibiotics DHPS-S is more fit in the presence of antibiotics than DHPS-R DHPS-S has a higher affinity for its normal substrates than DHPS-R DHPS-R likely has a nonsense or frameshift mutation
Transcribed Image Text:You are analyzing the DHPS gene and protein. DHPS catalyzes the first committed step in Folic Acid production, which is an essential precursor for nucleotide synthesis. DHPS is the target of the antibiotic sulfonamide, which blocks DHPS catalytic activity by acting as a competitive inhibitor. You also have mutant version of DHPS (called DHPS-R) that provides resistance to sulfonamides because it has much lower binding affinity to the antibiotic. Which statement do you anticipate to be true? Refer to the original DHSP gene version as DHSP-S. DHPS-R is a better enzyme overall than DHPS-S DHPS-R is more fit than DHPS-S in the absence of antibiotics DHPS-S is more fit in the presence of antibiotics than DHPS-R DHPS-S has a higher affinity for its normal substrates than DHPS-R DHPS-R likely has a nonsense or frameshift mutation
Expert Solution
steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Learning & Memory
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS