YOu are a Ciinical geneticist and have just spoken to your patient (labeled as "P'), who has a rare disorder known as the "Being- Awesome" disease. You have learned that this condition runs in his family, but he is the only one of his siblings affected by the disease. To explain why, you began by developing a pedigree of his family. 1. To identify the underlying mutations, you receive DNA samples from the six individuals in the third generation. Based on the pedigree, will you examine genomic DNA, mitochondrial DNA, exonic DNA or intronic DNA? Justify your choice.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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You are a clinical geneticist and have just spoken to your
patient (labeled as
"P'), who has a rare disorder known as the "Being-
Awesome" disease. You have learned that this condition
runs in his family, but he is the only one of his siblings
affected by the disease. To explain why, you began by
developing a pedigree of his family.
1. To identify the underlying mutations, you receive DNA
samples from the six individuals in the third generation.
Based on the pedigree, will you examine genomic DNA,
mitochondrial DNA,
exonic DNA or intronic DNA? Justify your choice.
Transcribed Image Text:You are a clinical geneticist and have just spoken to your patient (labeled as "P'), who has a rare disorder known as the "Being- Awesome" disease. You have learned that this condition runs in his family, but he is the only one of his siblings affected by the disease. To explain why, you began by developing a pedigree of his family. 1. To identify the underlying mutations, you receive DNA samples from the six individuals in the third generation. Based on the pedigree, will you examine genomic DNA, mitochondrial DNA, exonic DNA or intronic DNA? Justify your choice.
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