With RhoGAM -Second Rh+ fetus Rh- woman Rh antigen RhoGAM binds to fetal red blood cells leading to their removal before they can stimulate the mother's immune system to make antibodies. Second Rh+ fetus. Fetal red blood cells are not destroyed; mother will receive RhoGAM Rh+ fetus Without RhoGAM First Rh+ fetus. Baby's red blood cells with Rh+ antigen enter mother's circulation during birth. -Second Rh+ fetus -Anti-Rh IgG antibody FIGURE 17.4 Hemolytic Disease of the Newborn RhoGAM contains antibodies to Rh antigens Mother's immune system reacts, producing antibodies to Rh. Second Rh+ fetus. Mother's IgG antibodies cross the placenta; her anti-Rh antibodies bind to the baby's red blood cells, resulting in their destruction. and removes them from the mother's blood before her immune system can respond to them.

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.