With RhoGAM -Second Rh+ fetus Rh- woman Rh antigen RhoGAM binds to fetal red blood cells leading to their removal before they can stimulate the mother's immune system to make antibodies. Second Rh+ fetus. Fetal red blood cells are not destroyed; mother will receive RhoGAM Rh+ fetus Without RhoGAM First Rh+ fetus. Baby's red blood cells with Rh+ antigen enter mother's circulation during birth. -Second Rh+ fetus -Anti-Rh IgG antibody FIGURE 17.4 Hemolytic Disease of the Newborn RhoGAM contains antibodies to Rh antigens Mother's immune system reacts, producing antibodies to Rh. Second Rh+ fetus. Mother's IgG antibodies cross the placenta; her anti-Rh antibodies bind to the baby's red blood cells, resulting in their destruction. and removes them from the mother's blood before her immune system can respond to them.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Would a mother need RhoGAM again with a third Rh 1 fetus?

With RhoGAM
-Second
Rh+ fetus
Rh- woman
Rh antigen
RhoGAM binds to fetal red blood cells leading
to their removal before they can stimulate the
mother's immune system to make antibodies.
Second Rh+ fetus. Fetal red blood
cells are not destroyed; mother
will receive RhoGAM
Rh+ fetus
Without RhoGAM
First Rh+ fetus. Baby's red blood
cells with Rh+ antigen enter
mother's circulation during birth.
-Second
Rh+ fetus
-Anti-Rh IgG
antibody
FIGURE 17.4 Hemolytic Disease of the
Newborn RhoGAM contains antibodies to Rh antigens
Mother's immune system reacts,
producing antibodies to Rh.
Second Rh+ fetus. Mother's IgG antibodies cross
the placenta; her anti-Rh antibodies bind to the
baby's red blood cells, resulting in their destruction.
and removes them from the mother's blood before her
immune system can respond to them.
Transcribed Image Text:With RhoGAM -Second Rh+ fetus Rh- woman Rh antigen RhoGAM binds to fetal red blood cells leading to their removal before they can stimulate the mother's immune system to make antibodies. Second Rh+ fetus. Fetal red blood cells are not destroyed; mother will receive RhoGAM Rh+ fetus Without RhoGAM First Rh+ fetus. Baby's red blood cells with Rh+ antigen enter mother's circulation during birth. -Second Rh+ fetus -Anti-Rh IgG antibody FIGURE 17.4 Hemolytic Disease of the Newborn RhoGAM contains antibodies to Rh antigens Mother's immune system reacts, producing antibodies to Rh. Second Rh+ fetus. Mother's IgG antibodies cross the placenta; her anti-Rh antibodies bind to the baby's red blood cells, resulting in their destruction. and removes them from the mother's blood before her immune system can respond to them.
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