With reference to the molecules below, explain the factors which govern the water solubility and melting points and explain the differences in the values observed below. b) You are a chemical engineer working in a pharmaceutical manufacturing plant. You’ve been tasked with scaling up the synthesis of a potential drug candidate. From previous studies, you know the following information about reaction taking place: ΔHoreaction = -112.2kJ ΔS = -15.26JK-1mol-1 ΔG = -18.81kJ

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a) With reference to the molecules below, explain the factors which govern the water solubility and melting points and explain the differences in the values observed below. b) You are a chemical engineer working in a pharmaceutical manufacturing plant. You’ve been tasked with scaling up the synthesis of a potential drug candidate. From previous studies, you know the following information about reaction taking place: ΔHoreaction = -112.2kJ ΔS = -15.26JK-1mol-1 ΔG = -18.81kJ
Catechol
Resorcinol
Hydroquinone Benzoquinone
но
но-
но
OH
он
OH
Aqueous
solubility
(g/L)
461
1125
72
11
Melting
point (°C)
106
110
172
115
Transcribed Image Text:Catechol Resorcinol Hydroquinone Benzoquinone но но- но OH он OH Aqueous solubility (g/L) 461 1125 72 11 Melting point (°C) 106 110 172 115
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