Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
Related questions
Question
Why is bile acid binding resins not used for hypertrigliceridemia (high TG)? Please shortly answer at your own words.
Expert Solution
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Step 1
Bile acid resins or Bile acid sequestrants are group of resins that bind to the bile acid in the gastrointestinal tract and inhibit their functions such as lipid adsorption and bile acid reabsorption. The human liver synthesizes two bile acids namely, cholic acid (CA) and chenodeoxycholic acid (CDCA). These bile acid sequestrants are used in the treatment of hyperlipidemia, Bile acid malabsorption, pruritus, hyperthyroidism, hypercholesterolemia and dyslipidemia. The bile acid sequestrants along with the bound bile acid exit the body through feaces.
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