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Why does the addition of primary amines to aldehydes/ketones not work well at pH < 5? The amine gets protonated, making it no longer nucleophilic The -OH group can no longer be deprotonated to form a leaving group The amine gets deprotonated, making it no longer nucleophilic O The -OH group can no longer be protonated to form a leaving group

Why does the addition of primary amines to aldehydes/ketones not work well at pH < 5? The amine gets protonated, making it no longer nucleophilic The -OH group can no longer be deprotonated to form a leaving group The amine gets deprotonated, making it no longer nucleophilic O The -OH group can no longer be protonated to form a leaving group

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Why does the addition of primary amines to aldehydes/ketones not work well at pH < 5? The amine gets protonated, making it no longer nucleophilic The -OH group can no longer be deprotonated to form a leaving group The amine gets deprotonated, making it no longer nucleophilic The -OH group can no longer be protonated to form a leaving group
Transcribed Image Text:Why does the addition of primary amines to aldehydes/ketones not work well at pH < 5? The amine gets protonated, making it no longer nucleophilic The -OH group can no longer be deprotonated to form a leaving group The amine gets deprotonated, making it no longer nucleophilic The -OH group can no longer be protonated to form a leaving group
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