Why does histone deacetylase action tend to repress transcription?

Q: What are the transcription factors in eukaryotes? What is the role of transcription factors?…

A: Since you have posted multiple questions, we solve the first question for you. To get the remaining…

Q: What does histone acetylation favor?

A: The DNA (deoxyribonucleic acid) in cell is wrapped around proteins called histones. A DNA segment…

Q: How does binding of the trp corepressor to the trp repressor alter repressor function and…

A: The bacterial transcription unit containing more than one gene is known as an operon. An operon has…

Q: Transcriptionally active chromatin are generally found near the outer regions of the nucleus near…

A: The distribution of transcriptionally active chromatin throughout the nucleus is a complicated and…

Q: Why Transcription Requires Changes inChromatin Structure and NucleosomePosition?

A: Gene regulation is a mechanism which acts to either induce or repress the gene expression. It…

Q: What is meant by the term transcription factor modulation? List three general ways this can occur.

A: Transcription is the first step in central dogma of protein synthesis process. The conserved part in…

Q: What could be the effect  of a base substitution which prevents post-transcriptional removal of an…

A: A base substitution is a genetic mutation where a single nucleotide base is changed in the sequence…

Q: What is the major difference between transcriptional regulationin Archaea and eukaryotes?

A: Prokaryotes are the single cellular organism in which their nucleus is not confined and the absence…

Q: Why is TBP considered to be a universal transcription factor?

A: The TATA-binding protein is a general transcription factor that binds specifically to a DNA sequence…

Q: How does Transcription Factor IIH trigger the initiation of transcription?

A: Transcription is a process in which RNA is formed with the help of RNA polymerase enzyme which…

Q: If a repressor prevents TFIID from binding to the TATA box, why does this inhibit transcription?

A: TFIID - It is an important transcription factor, which plays a key role in the activity of RNA…

Q: Why transcription initiation requires the assembly of transcription regulatory proteins on DNA sites…

A: Transcription is the process by which an RNA is made from a segment of DNA. Transcription starts at…

Q: What is the difference in how mediator works with activation vs. repression of transcription?

A: Transcription refers to the mechanism in which the genetic information in DNA is transferred by RNA…

Q: How might nucleosome eviction affect transcription?

A: If the nucleosome is repositioned from its original place. Two possibilities might be seen- 1)The…

Q: Why transcription initiation requires the assembly of transcription regulatory proteins on DNA sites…

A: Silencer components are positioned upstream of the genes that they manage while negative regulatory…

Q: How histone deacetylases (HDACs) remove acetyl groups from histone tails ?

A: Histones are highly basic proteins that play an essential role in the packaging chromosomes.…

Q: When Histone modifications occur ?

A: A histone modification is a covalent post-translational modification (PTM) to histone proteins which…

Q: How does histone acetyltransferase affect nucleosome structure and transcription?

A: Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine residuals on histone…

Q: Explain the binding of transcription regulatory proteins to DNA ?

A: Transcriprion regulation is accompanied by gene regulatory proteins which bind with regulatory…

Q: Why are histone modifying enzymes important?

A: Chromosomes are thread-like structures that are present in the nucleus of the cell. The basic unit…

Q: What are histone demethylases.?

A: The genetic material of the cell lies inside the nucleus in the form of DNA. DNA is a long double…

Q: How is transcription controlled in prokaryotes?

A: DNA is transcribed to form mRNA via gene transcription. Prokaryotic transcription is less complex…

Q: Which type of transcriptional regulation is depicted?

A: Transception is a process in which RNA is synthesized with the help of template strand of DNA. The…

Q: Why is it important for a transcription factor/activator to have a high affinity for a specific DNA…

A: Transcription is a metabolic process in which DNA sequence of the gene is copied into an RNA…

Q: What is meant by the term histone code? With regard to gene regulation, what is the proposed role of…

A: The mechanism that acts to suppress or induces the gene expression is called gene regulation. These…

Q: What are general transcription factors? When do you expect to find them? What is a cis acting…

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: What are transcription factors How do they affect transcription?

A: The central dogma of molecular biology states than the DNA would undergo replication to make a copy…

Q: Explain how histone modifications affect transcription.

A: Histones are a family of basic proteins, which associate with deoxyribonucleic acid (DNA) in the…

Q: Describe events associated with the process of transcription in eukaryotic cells. How is the process…

A: RNA polymerase II transcribes protein-coding genes into messenger RNAs (mRNAs) that carry the…

Q: Explain how transcription is initiated in eukaryotic cells.

A: Eukaryotes are those organisms whose cells have a nucleus that is enclosed within a nuclear…

Q: What are the different terms used to describe the two strands of DNA involved in transcription?

A: Transcription is a process of formation of RNA. It is DNA dependent RNA synthesis process. Process…

Q: What effect would inhibitors of histone deacetylases have upon transcription? Group of answer…

A: Introduction :  The protein histones is very alkaline. In eukaryotic cells, they are located in the…

Q: in a eukaryote cell, what do we call the DNA sequence that the specific transcription factor binds…

A: The transcription is the process by which RNA is produced from the DNA template. In case of…

Q: What enzymes are involved in histone acetylation and deacetylations?

A: Deoxyribonucleic acid or DNA is enclosed around proteins as loose threads called the chromatin…