Which SN2 reaction is each pair is faster? А. Br H20 Br HO, OH Br Br OCH3 Oc .CI HO, B.

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**Title: Understanding SN2 Reaction Rates**

**Question:**  
Which SN2 reaction in each pair is faster?

---

**Section A:**

1. **Reaction 1:**
   - **Reactants:** 
     - 1-bromopentane
     - Water (\(H_2O\)) 
   - **Products:** 
     - Pentanol (\(OH_2^+\))
     - Bromide ion (\(Br^-\))

2. **Reaction 2:**
   - **Reactants:** 
     - 1-bromopentane
     - Hydroxide ion (\(OH^-\)) 
   - **Products:** 
     - Pentanol
     - Bromide ion (\(Br^-\))

**Section B:**

1. **Reaction 1:**
   - **Reactants:** 
     - 1-chloropentane
     - Methoxide ion (\(OCH_3^-\))
   - **Products:** 
     - Methoxy pentane
     - Chloride ion (\(Cl^-\))

2. **Reaction 2:**
   - **Reactants:** 
     - 1-iodopentane
     - Hydroxide ion (\(OH^-\))
   - **Products:** 
     - Pentanol
     - Iodide ion (\(I^-\))

**Explanation:**

In SN2 reactions, the rate is influenced by the nucleophile strength, the leaving group ability, and solvent effects. Generally, stronger nucleophiles and better leaving groups increase reaction rates.

- **Section A:** Compare the nucleophiles—\(OH^-\) is stronger than \(H_2O\), suggesting Reaction 2 is faster.
- **Section B:** Consider the leaving groups—iodide (\(I^-\)) is a better leaving group than chloride (\(Cl^-\)), indicating Reaction 2 is faster in this case as well.

**Conclusion:**

For faster SN2 reactions, choose strong nucleophiles and substrates with good leaving groups.
Transcribed Image Text:**Title: Understanding SN2 Reaction Rates** **Question:** Which SN2 reaction in each pair is faster? --- **Section A:** 1. **Reaction 1:** - **Reactants:** - 1-bromopentane - Water (\(H_2O\)) - **Products:** - Pentanol (\(OH_2^+\)) - Bromide ion (\(Br^-\)) 2. **Reaction 2:** - **Reactants:** - 1-bromopentane - Hydroxide ion (\(OH^-\)) - **Products:** - Pentanol - Bromide ion (\(Br^-\)) **Section B:** 1. **Reaction 1:** - **Reactants:** - 1-chloropentane - Methoxide ion (\(OCH_3^-\)) - **Products:** - Methoxy pentane - Chloride ion (\(Cl^-\)) 2. **Reaction 2:** - **Reactants:** - 1-iodopentane - Hydroxide ion (\(OH^-\)) - **Products:** - Pentanol - Iodide ion (\(I^-\)) **Explanation:** In SN2 reactions, the rate is influenced by the nucleophile strength, the leaving group ability, and solvent effects. Generally, stronger nucleophiles and better leaving groups increase reaction rates. - **Section A:** Compare the nucleophiles—\(OH^-\) is stronger than \(H_2O\), suggesting Reaction 2 is faster. - **Section B:** Consider the leaving groups—iodide (\(I^-\)) is a better leaving group than chloride (\(Cl^-\)), indicating Reaction 2 is faster in this case as well. **Conclusion:** For faster SN2 reactions, choose strong nucleophiles and substrates with good leaving groups.
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