Which one of the statements below best describes the mechanism of proton translocation by the Electron Transport System using a redox loop mechanism exemplified by the Q cycle? Protons located in the cytosol are translocated across the mitochondrial membrane into the matrix by altering pKa values of functional groups located on the inner and outer faces of the membrane within the protein channel. A redox reaction results in a H* and e- that are separated within the electron transport system and deposited on opposite sides of the outer mitochondrial membrane, with protons on the negative side. When the e-binds to cytochrome c, it results in dissociation of cytochrome c from complex II, which stimulates release of H* from complex IV, and thereby translocates protons and electrons separately. A redox reaction separating protons and electrons within complex III of the electron transport system, with the protons be translocated to the inter-membrane space and the electrons used to reduce Q.

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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Which one of the statements below best describes the mechanism of proton
translocation by the Electron Transport System using a redox loop
mechanism exemplified by the Q cycle?
Protons located in the cytosol are translocated across the mitochondrial
membrane into the matrix by altering pKą values of functional groups
located on the inner and outer faces of the membrane within the protein
channel.
A redox reaction results in a H* and e- that are separated within the
electron transport system and deposited on opposite sides of the outer
mitochondrial membrane, with protons on the negative side.
When the e-binds to cytochrome c, it results in dissociation of
cytochrome c from complex II, which stimulates release of H* from
complex IV, and thereby translocates protons and electrons separately.
A redox reaction separating protons and electrons within complex III of
the electron transport system, with the protons be translocated to the
inter-membrane space and the electrons used to reduce Q.
Transcribed Image Text:Which one of the statements below best describes the mechanism of proton translocation by the Electron Transport System using a redox loop mechanism exemplified by the Q cycle? Protons located in the cytosol are translocated across the mitochondrial membrane into the matrix by altering pKą values of functional groups located on the inner and outer faces of the membrane within the protein channel. A redox reaction results in a H* and e- that are separated within the electron transport system and deposited on opposite sides of the outer mitochondrial membrane, with protons on the negative side. When the e-binds to cytochrome c, it results in dissociation of cytochrome c from complex II, which stimulates release of H* from complex IV, and thereby translocates protons and electrons separately. A redox reaction separating protons and electrons within complex III of the electron transport system, with the protons be translocated to the inter-membrane space and the electrons used to reduce Q.
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