Which one of the following statements is incorrect? O Lithium diisopropylamide (LDA) is one of the most useful and common strong bases used in organic chemistry. o For a successful "crossed" condensation reaction of two carbonyl compounds that both have a-hydrogens, LDA is used to form the desired enolate ion and the other carbonyl compound is added slowly O Whereas a kinetic enolate anion is formed faster, a thermodynamic enolate anion is more stable. O HO¯ or RO¯ are good bases to form the enolate of an aldehyde or ketone in an alkylation reaction. o For a successful "crossed" condensation reaction, a carbonyl compound with a- hydrogens is added slowly to a solution of the carbonyl compound without a- hydrogens and a base.

Which one of the following statements is incorrect? O Lithium diisopropylamide (LDA) is one of the most useful and common strong bases used in organic chemistry. o For a successful "crossed" condensation reaction of two carbonyl compounds that both have a-hydrogens, LDA is used to form the desired enolate ion and the other carbonyl compound is added slowly O Whereas a kinetic enolate anion is formed faster, a thermodynamic enolate anion is more stable. O HO¯ or RO¯ are good bases to form the enolate of an aldehyde or ketone in an alkylation reaction. o For a successful "crossed" condensation reaction, a carbonyl compound with a- hydrogens is added slowly to a solution of the carbonyl compound without a- hydrogens and a base.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Concept explainers

Catalysis and Enzymatic Reactions

Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.

Lock And Key Model

The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.

Question

Which one of the following statements is incorrect?
O Lithium diisopropylamide (LDA) is one of the most useful and common strong
bases used in organic chemistry.
O For a successful "crossed" condensation reaction of two carbonyl compounds that
both have a-hydrogens, LDA is used to form the desired enolate ion and the other
carbonyl compound is added slowly
O Whereas a kinetic enolate anion is formed faster, a thermodynamic enolate anion
is more stable.
O HO or RO¯ are good bases to form the enolate of an aldehyde or ketone in an
alkylation reaction.
O For a successful "crossed" condensation reaction, a carbonyl compound with a-
hydrogens is added slowly to a solution of the carbonyl compound without a-
hydrogens and a base.

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