Which one of the following Starting Material شیده tBu || Br tBu OH is expected to form an epoxide fastest? NaH Epoxide Product Br OH THE tBu OIV O All will react at the same rate. O 111 OII 01 OH 'Br IV (Bu OH Br
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![Which one of the following is expected to form an epoxide fastest?
NaH
Starting Material
Epoxide Product
tBu
||
Br tBu
011
OI
OH
Br
THE
tBu
OIV
O All will react at the same rate.
O III
OH
'Br
IV
(Bu,
OH
Br](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fc1eb37bf-1045-43dd-a351-de2d9ca4d2a5%2F7f5ee622-7df6-4f51-8e65-bef1a2e3e379%2Fhheyt6d_processed.jpeg&w=3840&q=75)
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