Which of the following statements about "Focused transcription initiation", "Dispersed transcription initiation" and "transcription start sites" (TSS) are correct.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Transcription is the process by which the DNA sequence is "transcribed" into RNA sequence. It is the first step in gene regulation. Protein is what gives living organisms its form. The DNA has a lot of material, of which genes are a small part. These genes or protein coding regions alone are copied into RNA, which is then translated into proteins.
RNAs are of many types. mRNA or messenger RNA is the RNA, as the name suggests, carries the protein coding information from the DNA to the proteins.
Transcription involves the following steps:
- Initiation: Unwinding of DNA and binding of the RNA polymerase to the promoter
- Elongation: The RNA polymerase moves forwards generating the RNA strand
- Termination: This step varies between prokaryotes and eukaryotes. In eukaryotes, there is an additional step of adding a polyA tail
- Post transcriptional modifications: This includes splicing out the introns, addition of 5' G-cap
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