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Which of the following results is consistent with muscle damage and necrosis of myoctes seen in rhabdomyolysis? (select all that apply) O Increased Serum calcium O Increased Serum Creatine kinase O Increased myoglobinuria O Decreased Alkaline Phosphatase

Which of the following results is consistent with muscle damage and necrosis of myoctes seen in rhabdomyolysis? (select all that apply) O Increased Serum calcium O Increased Serum Creatine kinase O Increased myoglobinuria O Decreased Alkaline Phosphatase

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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**Understanding Rhabdomyolysis and Laboratory Findings** **Question:** Which of the following results is consistent with muscle damage and necrosis of myocytes seen in rhabdomyolysis? (Select all that apply) - [ ] Increased Serum calcium - [ ] Increased Serum Creatine kinase - [ ] Increased myoglobinuria - [ ] Decreased Alkaline Phosphatase **Explanation:** Rhabdomyolysis is a serious syndrome resulting from the direct or indirect muscle injury. It involves the rapid breakdown of damaged skeletal muscle. Signs and laboratory findings consistent with rhabdomyolysis generally include: 1. **Increased Serum Creatine Kinase:** This enzyme is released from damaged muscle tissue and is a key marker for muscle injury. 2. **Increased Myoglobinuria:** Myoglobin from the damaged muscles can be released into the urine, causing myoglobinuria. 3. **Increased serum potassium levels** (not listed): This can occur due to the release of potassium from ruptured muscle cells. 4. **Changes in calcium levels**: Initially, the serum calcium levels might decrease but can later increase. While the question options do not list serum potassium or the dynamic changes in calcium, options concerned with elevated serum creatine kinase and increased myoglobinuria are consistent with rhabdomyolysis. It is also important to note that decreased alkaline phosphatase is not typically associated with rhabdomyolysis, nor is increased serum calcium an immediate finding; however, late-phase rhabdomyolysis could potentially show altered calcium levels.
Transcribed Image Text:**Understanding Rhabdomyolysis and Laboratory Findings** **Question:** Which of the following results is consistent with muscle damage and necrosis of myocytes seen in rhabdomyolysis? (Select all that apply) - [ ] Increased Serum calcium - [ ] Increased Serum Creatine kinase - [ ] Increased myoglobinuria - [ ] Decreased Alkaline Phosphatase **Explanation:** Rhabdomyolysis is a serious syndrome resulting from the direct or indirect muscle injury. It involves the rapid breakdown of damaged skeletal muscle. Signs and laboratory findings consistent with rhabdomyolysis generally include: 1. **Increased Serum Creatine Kinase:** This enzyme is released from damaged muscle tissue and is a key marker for muscle injury. 2. **Increased Myoglobinuria:** Myoglobin from the damaged muscles can be released into the urine, causing myoglobinuria. 3. **Increased serum potassium levels** (not listed): This can occur due to the release of potassium from ruptured muscle cells. 4. **Changes in calcium levels**: Initially, the serum calcium levels might decrease but can later increase. While the question options do not list serum potassium or the dynamic changes in calcium, options concerned with elevated serum creatine kinase and increased myoglobinuria are consistent with rhabdomyolysis. It is also important to note that decreased alkaline phosphatase is not typically associated with rhabdomyolysis, nor is increased serum calcium an immediate finding; however, late-phase rhabdomyolysis could potentially show altered calcium levels.
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