Which of the following reaction schemes would make the alcohol hown below? Select any that apply. OH 0 0 & H + CH3MgBr CH3MgBr MgBr HMgBr 2) H₂0¹ 2) H30¹ 2) H30* 2) H30*
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
Please help with the acetal/grignard reaction
![### Question 1
**Prompt:**
Which of the following reaction schemes would make the alcohol shown below? Select any that apply.
**Target Alcohol Structure:**
The structure shown is a six-membered cyclohexane ring with a hydroxyl group (OH) attached to it, as well as an adjacent methyl group.
**Reaction Schemes:**
1. **Option A:**
- Reactants: Ketone (cyclohexanone) + CH₃MgBr (methylmagnesium bromide)
- Conditions: H₃O⁺ (acidic work-up)
- Outcome: Reacts to form the secondary alcohol shown.
2. **Option B:**
- Reactants: Ketone (cyclopentanone with an additional methyl group) + CH₃MgBr
- Conditions: H₃O⁺
- No reaction forming the shown alcohol.
3. **Option C:**
- Reactants: Formaldehyde (HCHO) + cyclohexylmagnesium bromide
- Conditions: H₃O⁺
- Outcome: Reacts but does not form the target alcohol.
4. **Option D:**
- Reactants: Cyclohexanone + H-MgBr
- Conditions: H₃O⁺
- Outcome: This reaction forms the desired alcohol.
**Correct Options:**
- Option A
- Option D
These reactions correctly form the alcohol given in the prompt by utilizing a Grignard reagent in an addition reaction followed by an acidic work-up.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F75ec21af-4b38-4f4d-bc0b-8ea95ad2f0d8%2Fd0b5ce5b-afff-4932-91fa-1a56ec704900%2Famvf0zk_processed.jpeg&w=3840&q=75)
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