Which of the following DNA mutations is almost certain to result in a shorter than normal protein?

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Use the following mRNA codon key as needed to answer this question:
GCC Alanine
AAU Asparagine
CCU Proline
GGA Glycine
UGG Tryptophan
UGA "Stop" (no amino acid)
GAA Glutamic acid
GAG Glutamic acid
AGG Arginine
CCC Proline
CAU Histidine
The following DNA sequence (coding strand) occurs near the middle of the coding region of a gene.
DNA:
50
mRNA:
55
5'-AATGAATGGGAGCCTGAAGGAG--3'
50
The corresponding mRNA sequence is shown below. Note that the coding strand of DNA has the same sequence as
the mRNA, except that there are U's in the mRNA where there are T's in the DNA. The first triplet of nucleotides
AAU (underlined) is in frame for coding, and encodes Asparagine as the codon table above indicates.
60
55
65
60
C→A at position 58
65
5'-AAUGAAUGGGAGCCUGAAGGAG --3'
Which of the following DNA mutations is almost certain to result in a shorter than normal protein?
Transcribed Image Text:Use the following mRNA codon key as needed to answer this question: GCC Alanine AAU Asparagine CCU Proline GGA Glycine UGG Tryptophan UGA "Stop" (no amino acid) GAA Glutamic acid GAG Glutamic acid AGG Arginine CCC Proline CAU Histidine The following DNA sequence (coding strand) occurs near the middle of the coding region of a gene. DNA: 50 mRNA: 55 5'-AATGAATGGGAGCCTGAAGGAG--3' 50 The corresponding mRNA sequence is shown below. Note that the coding strand of DNA has the same sequence as the mRNA, except that there are U's in the mRNA where there are T's in the DNA. The first triplet of nucleotides AAU (underlined) is in frame for coding, and encodes Asparagine as the codon table above indicates. 60 55 65 60 C→A at position 58 65 5'-AAUGAAUGGGAGCCUGAAGGAG --3' Which of the following DNA mutations is almost certain to result in a shorter than normal protein?
CAU Histidine
The following DNA sequence (coding strand) occurs near the middle of the coding region of a gene.
DNA:
50
mRNA:
55
5'-AATGAATGGGAGCCTGAAGGAG --3'
50
The corresponding mRNA sequence is shown below. Note that the coding strand of DNA has the same sequence as
the mRNA, except that there are U's in the mRNA where there are T's in the DNA. The first triplet of nucleotides
AAU (underlined) is in frame for coding, and encodes Asparagine as the codon table above indicates.
55
C-A at po
60
ition 58
5'-AAUGAAUGGGAGCCUGAAGGAG --3'
G→A at position 53
65
Which of the following DNA mutations is almost certain to result in a shorter than normal protein?
None of the above
60
A→G at position 50
65
Transcribed Image Text:CAU Histidine The following DNA sequence (coding strand) occurs near the middle of the coding region of a gene. DNA: 50 mRNA: 55 5'-AATGAATGGGAGCCTGAAGGAG --3' 50 The corresponding mRNA sequence is shown below. Note that the coding strand of DNA has the same sequence as the mRNA, except that there are U's in the mRNA where there are T's in the DNA. The first triplet of nucleotides AAU (underlined) is in frame for coding, and encodes Asparagine as the codon table above indicates. 55 C-A at po 60 ition 58 5'-AAUGAAUGGGAGCCUGAAGGAG --3' G→A at position 53 65 Which of the following DNA mutations is almost certain to result in a shorter than normal protein? None of the above 60 A→G at position 50 65
Expert Solution
Step 1: Analyzing the DNA Sequence and mRNA Sequence

In the present circumstance, we possess a DNA sequence and its equivalent mRNA sequence. It is essential to ascertain the specific DNA mutation that is very likely to lead to a protein of reduced length compared to the standard norm.

The mRNA sequence is as follows: S-AAUGAAUGGGAGCCUGAAGGAG--3.

The codon AAU is used for the coding and encoding of Asparagine.














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