Which of the following compounds are chiral? Draw each compound in its most symmetric con- formation, star (*) any asymmetric carbon atoms, and draw any mirror planes. Label any meso compounds. You may use Fischer projections if you prefer. (a) meso-2,3-dibromo-2,3-dichlorobutane (b) (±)-2,3-dibromo-2,3-dichlorobutane (c) (2R,3S)-2-bromo-3-chlorobutane (d) (2R,3S)-2,3-dibromobutane (e) (R, R)-2,3-dibromobutane (1) CHO H -OH -H CH₂OH HO H Br H CH, H CH₂ H - Br (h) H Br CH, H H CH₂ H Br
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
![**Problem 5-21**
**Objective:** Identify which of the following compounds are chiral. Draw each compound in its most symmetric conformation, mark (*) any asymmetric carbon atoms, and draw any mirror planes. Label any meso compounds. You may use Fischer projections if you prefer.
**Compounds to Analyze:**
(a) meso-2,3-dibromo-2,3-dichlorobutane
(b) (±)-2,3-dibromo-2,3-dichlorobutane
(c) (2R,3S)-2-bromo-3-chlorobutane
(d) (2R,3S)-2,3-dibromobutane
(e) (R,R)-2,3-dibromobutane
**References:**
- Diagrams (f), (g), and (*h) are provided below descriptions.
**Diagram Descriptions:**
- Diagram (f): A Fischer projection of a sugar with an aldehyde group (CHO) at the top, two hydroxyl groups (OH) on the left and right on the second carbon, and a CH₂OH group at the bottom. This structure is a typical projection to illustrate stereochemistry in sugars.
- Diagram (g): A chair conformation showing multiple carbon atoms with hydrogen and methyl (CH₃) groups attached. There are bromine (Br) atoms shown on some carbon positions. This representation helps visualize the spatial arrangement in cyclohexane derivatives.
- Diagram (*h): Another chair conformation, similar to diagram (g), highlighting specific carbon atoms with bromine (Br) and methyl (CH₃) groups, indicating asymmetric centers with an asterisk (*). This emphasizes the analysis of chirality and mirror symmetry in the cyclic structure.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F2950fafb-198b-44f1-a559-ce3dae66bd5f%2F38b06e2a-7340-4251-8f36-f6a7366ff13c%2Fjmaym5q_processed.jpeg&w=3840&q=75)
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