Which of the following combination has the slowest esterification reaction rate? 1. CH3CH2CH2COOH IL (CH3)2CHCOOH I. CH3CH2CH2CH2CH2OH IV. (CH3)3CCH2OH II & II O 1& II O 1& IV O I & IV O 1& 1 O & IV
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
![QUESTION 17
Which of the following is the correct order of mechanism steps for Fischer esterification?
[3] Protonation of one hydroxyl group in the intermediate by acid
[b] Protonation on carboxylic acid
a Hydrogen connected to the alcohol oxygen deprotonated by another alcohol
[d) Nucieophilic attack on the protonated carboxylic acid by an alcohol
re) Deprotonation by an alcohol
A Loss of protonated hydroxyl group as a water molecule & formation of carbon-oxygen double bond
[b]- (a)--(a]- [d] (d
(a] [b)-(- (d]- n-(e)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F4822f11c-199a-4554-b9e6-0b80c71c7687%2Fca38c226-c1e2-4df4-9ada-7d043c73b607%2Fukxx28y_processed.jpeg&w=3840&q=75)
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