Which of the following acid-base systems is NOT suitable to prepare a buffer with a pH 7.4? MTS Tris (tris(hydroxymethyl)aminomethane): pK₁ = 8.0 Phosphate: pKal = 2.16 pKa2 = 7.21 pK₁3 = 12.32 Leucine: pKal= 2.328, pKa2=9.744 HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid): pKal = 3.0, pka2 = 7.5
Which of the following acid-base systems is NOT suitable to prepare a buffer with a pH 7.4? MTS Tris (tris(hydroxymethyl)aminomethane): pK₁ = 8.0 Phosphate: pKal = 2.16 pKa2 = 7.21 pK₁3 = 12.32 Leucine: pKal= 2.328, pKa2=9.744 HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid): pKal = 3.0, pka2 = 7.5
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
Related questions
Question
![5. Which of the following acid-base systems is NOT suitable to prepare a buffer with a pH 7.4?
MTS88,0
MACELI
A. Tris (tris(hydroxymethyl)aminomethane): pKa = 8.0
3. Phosphate: pKal = 2.16 pKa2 = 7.21 pka3 = 12.32
C. Leucine: pKal= 2.328, pKa2=9.744
D. HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid): pKal = 3.0, pKa2 = 7.5](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ff3c0899a-5c62-4a86-a39c-5b160af6a916%2Ffe4e3f57-5987-4154-acc5-e91b9049daee%2F3assj_processed.jpeg&w=3840&q=75)
Transcribed Image Text:5. Which of the following acid-base systems is NOT suitable to prepare a buffer with a pH 7.4?
MTS88,0
MACELI
A. Tris (tris(hydroxymethyl)aminomethane): pKa = 8.0
3. Phosphate: pKal = 2.16 pKa2 = 7.21 pka3 = 12.32
C. Leucine: pKal= 2.328, pKa2=9.744
D. HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid): pKal = 3.0, pKa2 = 7.5
Expert Solution
![](/static/compass_v2/shared-icons/check-mark.png)
Step 1
The main objective while selecting the acid-base system is to choose the buffer whose pKa values are closest to the target pH.
Step by step
Solved in 3 steps
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781305957404/9781305957404_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781259911156/9781259911156_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
![Principles of Instrumental Analysis](https://www.bartleby.com/isbn_cover_images/9781305577213/9781305577213_smallCoverImage.gif)
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781305957404/9781305957404_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781259911156/9781259911156_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
![Principles of Instrumental Analysis](https://www.bartleby.com/isbn_cover_images/9781305577213/9781305577213_smallCoverImage.gif)
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
![Organic Chemistry](https://www.bartleby.com/isbn_cover_images/9780078021558/9780078021558_smallCoverImage.gif)
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
![Chemistry: Principles and Reactions](https://www.bartleby.com/isbn_cover_images/9781305079373/9781305079373_smallCoverImage.gif)
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
![Elementary Principles of Chemical Processes, Bind…](https://www.bartleby.com/isbn_cover_images/9781118431221/9781118431221_smallCoverImage.gif)
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY