Which is the proper label of configuration for this molecule? R- S- cis- HO- 大 Et A) B) C) D) trans- E) No label of configuration is needed 4

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Which is the proper label of configuration for
this molecule?
R-
S-
HO-
cis-
H
A)
B)
C)
D)
trans-
E) No label of configuration is needed
Et
4
Transcribed Image Text:Which is the proper label of configuration for this molecule? R- S- HO- cis- H A) B) C) D) trans- E) No label of configuration is needed Et 4
Expert Solution
Step 1: Cahn-Ingold-Prelog rules to assign the absolute configuration

First, identify the chiral centers present in the molecule

Assign priorities to the attached atoms/groups based on the atomic number of the attached atom.

If the first attached atom is the same proceed in the chain till the point of difference is obtained.

After assigning the priority, keep the least priority atom/group below the plane, If the priority order is clockwise the configuration is R and if it is anti-clockwise, the configuration is S.

If the least priority atom/group above the plane, if the priority order is clockwise the configuration is S and if it is anti-clockwise, the configuration is R.

cis- or trans- configuration can be assigned for those compounds which can have restricted rotation about double bond or ring

The proper label of configuration for the given molecule


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