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Which is the major product(s) of the following reaction? Br LDA THE

Which is the major product(s) of the following reaction? Br LDA THE

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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**Question:** Which is the major product(s) of the following reaction? **Image Description:** The image depicts a chemical reaction involving a cyclohexane ring with a bromine (Br) substituent attached to one of the carbon atoms. The bromine atom is shown as a wedge, indicating it is coming out of the plane of the ring. A dashed line (stereochemistry) is leading to an LDA (lithium diisopropylamide) reagent and THF (tetrahydrofuran), both labeled on the arrow pointing to the right. **Explanation:** In the reaction, LDA acts as a strong base to abstract a proton, leading to the formation of a more substituted alkene by elimination (E2 mechanism). The major product will be the one where the double bond is more substituted and stabilized according to Zaitsev's rule.
Transcribed Image Text:**Question:** Which is the major product(s) of the following reaction? **Image Description:** The image depicts a chemical reaction involving a cyclohexane ring with a bromine (Br) substituent attached to one of the carbon atoms. The bromine atom is shown as a wedge, indicating it is coming out of the plane of the ring. A dashed line (stereochemistry) is leading to an LDA (lithium diisopropylamide) reagent and THF (tetrahydrofuran), both labeled on the arrow pointing to the right. **Explanation:** In the reaction, LDA acts as a strong base to abstract a proton, leading to the formation of a more substituted alkene by elimination (E2 mechanism). The major product will be the one where the double bond is more substituted and stabilized according to Zaitsev's rule.
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