Chapter16: Specialized Nutrition Support: Enteral And Parenteral Nutrition
Section: Chapter Questions
Problem 9SC
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Question
Which has the greatest buffering capacity at a physiological ph?
Tyr-Lys-Met
Gly-Pro-Ara
Asp-Trp-tvr
V Asp-His-Glu
Leu-Val-Phe
His-Ala-His
Expert Solution
INTRODUCTION AND EXPLANATION
By consuming the buffer, a buffer prevents pH changes caused by the addition of an acid or base. The pH won't alter significantly as long as the buffer hasn't fully reacted. As the buffer is depleted, it becomes less resistant to change, causing the pH change to increase (or fall) more dramatically.
Over the pH = pKa 1 range, buffers are typically effective.
The highest resistance to pH change is achieved by a buffer when the pH equals pKa, which is defined as maximum buffer capacity. The buffering region is greatest in the region where pH = pKa.
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