What must take place before an activated fatty acid undergoes β oxidation?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question
What must take place before an activated fatty acid undergoes β oxidation?
Expert Solution

Step 1
The main reaction to produce energy using lipids is in the fatty acid spiral. The beta oxidation of fatty acids occurs by the removal of two carbons at a time as acetyl CoA in a spiral type reaction. These reactions occur in the mitochondria and are closely associated with the ETC to produce energy in the form of ATP.
The overall reaction is:
fatty acid CoA + NAD+ + FAD ---> acetyl CoA + NADH + H+ + FADH2
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